Wu-Lin Zuo
Overview
Explore the profile of Wu-Lin Zuo including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
385
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0
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Recent Articles
1.
Zuo W, Rostami M, LeBlanc M, Kaner R, OBeirne S, Mezey J, et al.
PLoS One
. 2020 Sep;
15(9):e0237529.
PMID: 32941426
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. "Bronchiolization", characterized by ectopic appearance of airway epithelial cells in the alveolar...
2.
Zuo W, Rostami M, Shenoy S, LeBlanc M, Salit J, Strulovici-Barel Y, et al.
Respir Res
. 2020 Jul;
21(1):200.
PMID: 32727470
Background: The human small airway epithelium (SAE) plays a central role in the early events in the pathogenesis of most inherited and acquired lung disorders. Little is known about the...
3.
Zhu D, Rostami M, Zuo W, Leopold P, Crystal R
Hum Gene Ther
. 2020 Mar;
31(9-10):590-604.
PMID: 32143547
Capitalizing on liver tropism of adeno-associated viral (AAV) vectors, intravenous vector administration is commonly used to genetically modify hepatocytes, a strategy currently in clinical trials for a number of liver-based...
4.
Zuo W, Yang J, Strulovici-Barel Y, Salit J, Rostami M, Mezey J, et al.
Eur Respir J
. 2019 Feb;
53(5).
PMID: 30705127
Airway remodelling in chronic obstructive pulmonary disease (COPD) originates, in part, from smoking-induced changes in airway basal stem/progenitor cells (BCs). Based on the knowledge that bone morphogenetic protein 4 (BMP4)...
5.
Zuo W, Shenoy S, Li S, OBeirne S, Strulovici-Barel Y, Leopold P, et al.
Am J Respir Crit Care Med
. 2018 Jun;
198(11):1375-1388.
PMID: 29874100
Rationale: Little is known about human club cells, dome-shaped cells with dense cytoplasmic granules and microvilli that represent the major secretory cells of the human small airways (at least sixth-generation...
6.
Yang D, Xu J, Zhu J, Zhang Y, Xu J, Sun Q, et al.
Biochem Biophys Res Commun
. 2017 Apr;
487(3):517-524.
PMID: 28412354
Several studies have implicated estrogen and the estrogen receptor (ER) in the pathogenesis of benign prostatic hyperplasia (BPH); however, the mechanism underlying this effect remains elusive. In the present study,...
7.
Yang J, Zuo W, Fukui T, Chao I, Gomi K, Lee B, et al.
Am J Respir Crit Care Med
. 2017 Mar;
196(3):340-352.
PMID: 28345955
Rationale: Small airways are the primary site of pathologic changes in chronic obstructive pulmonary disease (COPD), the major smoking-induced lung disorder. Objectives: On the basis of the concept of proximal-distal...
8.
Zuo W, Yang J, Gomi K, Chao I, Crystal R, Shaykhiev R
Stem Cells
. 2016 Oct;
35(3):824-837.
PMID: 27709733
The airway epithelium of cigarette smokers undergoes dramatic remodeling with hyperplasia of basal cells (BC) and mucus-producing cells, squamous metaplasia, altered ciliated cell differentiation and decreased junctional barrier integrity, relevant...
9.
Zhou H, Brekman A, Zuo W, Ou X, Shaykhiev R, Agosto-Perez F, et al.
J Immunol
. 2016 Mar;
196(7):3159-67.
PMID: 26927796
In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected expression of POU domain class 2-associating factor...
10.
Shaykhiev R, Zuo W, Chao I, Fukui T, Witover B, Brekman A, et al.
Proc Natl Acad Sci U S A
. 2013 Jul;
110(29):12102-7.
PMID: 23818594
The airway epithelium of smokers acquires pathological phenotypes, including basal cell (BC) and/or goblet cell hyperplasia, squamous metaplasia, structural and functional abnormalities of ciliated cells, decreased number of secretoglobin (SCGB1A1)-expressing...