Wouter Peelaerts
Overview
Explore the profile of Wouter Peelaerts including associated specialties, affiliations and a list of published articles.
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13
Citations
292
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Recent Articles
1.
Mercado G, Clabout A, Howland V, Arkin E, Janer A, Plessers D, et al.
J Parkinsons Dis
. 2025 Feb;
14(8):1559-1574.
PMID: 39957188
Background: Urinary tract infections (UTIs) have recently been linked to the onset of multiple synucleinopathies including Parkinson's disease (PD) and multiple system atrophy (MSA). UTIs are more common in people...
2.
Mercado G, Kaeufer C, Richter F, Peelaerts W
J Parkinsons Dis
. 2024 Sep;
14(7):1301-1329.
PMID: 39331109
Increasing evidence suggests a potential role for infectious pathogens in the etiology of synucleinopathies, a group of age-related neurodegenerative disorders including Parkinson's disease (PD), multiple system atrophy and dementia with...
3.
Peelaerts W, Baekelandt V
Neurotherapeutics
. 2023 Apr;
20(1):67-82.
PMID: 37052776
Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are termed synucleinopathies, disorders that are characterized by the intracellular aggregation of the protein ɑ-synuclein. The cellular...
4.
Peelaerts W, Mercado G, George S, Villumsen M, Kasen A, Aguileta M, et al.
Acta Neuropathol
. 2023 Mar;
145(5):541-559.
PMID: 36991261
Symptoms in the urogenital organs are common in multiple system atrophy (MSA), also in the years preceding the MSA diagnosis. It is unknown how MSA is triggered and these observations...
5.
Peelaerts W, Bergkvist L, George S, Johnson M, Meyerdirk L, Schulz E, et al.
Free Neuropathol
. 2022 Feb;
1.
PMID: 35224554
Epidemiological studies suggest a link between type-2 diabetes and Parkinson's disease (PD) risk. Treatment of type-2 diabetes with insulin sensitizing drugs lowers the risk of PD. We previously showed that...
6.
Torre-Muruzabal T, Van der Perren A, Coens A, Gelders G, Janer A, Camacho-Garcia S, et al.
Brain
. 2022 Feb;
146(1):237-251.
PMID: 35170728
Multiple system atrophy is a progressive neurodegenerative disease with prominent autonomic and motor features. During early stages, different subtypes of the disease are distinguished by their predominant parkinsonian or cerebellar...
7.
Marmion D, Peelaerts W, Kordower J
J Neural Transm (Vienna)
. 2021 Oct;
128(10):1507-1527.
PMID: 34613484
Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA), and dysautonomia with cerebellar ataxia or parkinsonian motor features. Isolated autonomic dysfunction with...
8.
Peelaerts W, Brito F, Van den Haute C, Janer A, Steiner J, Brundin P, et al.
Hum Gene Ther
. 2021 May;
32(11-12):616-627.
PMID: 34006117
Several neurodegenerative disorders are characterized by oligodendroglial pathology and myelin loss. Oligodendrogliopathies are a group of rare diseases for which there currently is no therapy. Gene delivery through viral vectors...
9.
George S, Tyson T, Rey N, Sheridan R, Peelaerts W, Becker K, et al.
J Parkinsons Dis
. 2021 Feb;
11(2):585-603.
PMID: 33579871
Background: α-Synuclein (α-syn) is the predominant protein in Lewy-body inclusions, which are pathological hallmarks of α-synucleinopathies, such as Parkinson's disease (PD) and multiple system atrophy (MSA). Other hallmarks include activation...
10.
Van der Perren A, Gelders G, Fenyi A, Bousset L, Brito F, Peelaerts W, et al.
Acta Neuropathol
. 2020 May;
139(6):977-1000.
PMID: 32356200
Synucleinopathies, such as Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), are defined by the presence of α-synuclein (αSYN) aggregates throughout the nervous system but...