Wouter Claeys
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Explore the profile of Wouter Claeys including associated specialties, affiliations and a list of published articles.
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9
Citations
52
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Recent Articles
1.
Claeys W, Geerts A, Van Hoecke L, Van Steenkiste C, Vandenbroucke R
Neural Regen Res
. 2024 Dec;
PMID: 39688562
Hepatic encephalopathy, defined as neuropsychiatric dysfunction secondary to liver disease, is a frequent decompensating event in cirrhosis. Its clinical impact is highlighted by a notable increase in patient mortality rates...
2.
Van Hoecke L, Castelein J, Xie J, Van Acker L, Van Imschoot G, Van Wonterghem E, et al.
Brain Behav Immun
. 2023 Dec;
117:122-134.
PMID: 38142916
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by a concerning rise in prevalence. It is projected that the number of affected individuals will reach a staggering 150 million...
3.
Claeys W, Verhaege D, Van Imschoot G, Van Wonterghem E, Van Acker L, Amelinck L, et al.
Front Immunol
. 2023 Dec;
14:1283711.
PMID: 38077359
Microglia, the resident macrophages of the central nervous system (CNS), play a critical role in CNS homeostasis and neuroinflammation. Pexidartinib (PLX3397), a colony-stimulating factor 1 (CSF1) receptor inhibitor, is widely...
4.
Claeys W, Van Hoecke L, Lernout H, De Nolf C, Van Imschoot G, Van Wonterghem E, et al.
J Neuroinflammation
. 2023 May;
20(1):130.
PMID: 37248507
Hepatic encephalopathy (HE) is a common complication of liver cirrhosis, associated with high morbidity and mortality, for which no brain-targeted therapies exist at present. The interplay between hyperammonemia and inflammation...
5.
Claeys W, Van Hoecke L, Geerts A, Van Vlierberghe H, Lefere S, Van Imschoot G, et al.
Sci Rep
. 2022 Oct;
12(1):17558.
PMID: 36266427
Hepatic encephalopathy (HE) is a common complication of chronic liver disease, characterized by an altered mental state and hyperammonemia. Insight into the brain pathophysiology of HE is limited due to...
6.
Van Hoecke L, Van Cauwenberghe C, Borger V, Bruggeman A, Castelein J, Van Imschoot G, et al.
Biomedicines
. 2021 Dec;
9(12).
PMID: 34944681
Niemann-Pick type C (NPC) disease is a rare neurovisceral lipid storage disease with progressive neurodegeneration, leading to premature death. The disease is caused by loss-of-function mutations either in the or...
7.
Van Hoecke L, Van Cauwenberghe C, Dominko K, Van Imschoot G, Van Wonterghem E, Castelein J, et al.
Front Cell Neurosci
. 2021 Nov;
15:757482.
PMID: 34720883
Niemann-Pick type C (NPC) disease, sometimes called childhood Alzheimer's, is a rare neurovisceral lipid storage disease with progressive neurodegeneration leading to premature death. The disease is caused by loss-of-function mutations...
8.
Claeys W, Van Hoecke L, Lefere S, Geerts A, Verhelst X, Van Vlierberghe H, et al.
JHEP Rep
. 2021 Oct;
3(5):100352.
PMID: 34611619
Hepatic encephalopathy (HE) is a neurological complication of hepatic dysfunction and portosystemic shunting. It is highly prevalent in patients with cirrhosis and is associated with poor outcomes. New insights into...
9.
Claeys W, Delie A, Smeets P, De Scheerder M, Degroote H, Verhelst X, et al.
Clin Case Rep
. 2021 Aug;
9(8):e04448.
PMID: 34429979
Focal eosinophilic infiltration (FEI) of the liver shares imaging characteristics with malignant hepatic lesions but should be suspected when concomitantly observing eosinophilia. While in itself benign, the cause of FEI...