Griet Van Imschoot
Overview
Explore the profile of Griet Van Imschoot including associated specialties, affiliations and a list of published articles.
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26
Citations
498
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Recent Articles
1.
Burgelman M, Dujardin P, Willems A, Hochepied T, Van Imschoot G, Van Wonterghem E, et al.
J Extracell Biol
. 2024 Nov;
3(11):e70015.
PMID: 39525277
Extracellular vesicles (EVs) are pivotal in intercellular communication, impacting diverse physiological and pathological processes. Current in vitro EV biogenesis studies often utilize pharmacological inhibitors, inducing off-target effects and overlooking cell-specific...
2.
Vandendriessche C, Bruggeman A, Foroozandeh J, Van Hoecke L, Dujardin P, Xie J, et al.
eNeuro
. 2024 Feb;
11(3).
PMID: 38383588
Parkinson's disease (PD) patients harbor seeding-competent α-synuclein (α-syn) in their cerebrospinal fluid (CSF), which is mainly produced by the choroid plexus (ChP). Nonetheless, little is known about the role of...
3.
Van Hoecke L, Castelein J, Xie J, Van Acker L, Van Imschoot G, Van Wonterghem E, et al.
Brain Behav Immun
. 2023 Dec;
117:122-134.
PMID: 38142916
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by a concerning rise in prevalence. It is projected that the number of affected individuals will reach a staggering 150 million...
4.
Claeys W, Verhaege D, Van Imschoot G, Van Wonterghem E, Van Acker L, Amelinck L, et al.
Front Immunol
. 2023 Dec;
14:1283711.
PMID: 38077359
Microglia, the resident macrophages of the central nervous system (CNS), play a critical role in CNS homeostasis and neuroinflammation. Pexidartinib (PLX3397), a colony-stimulating factor 1 (CSF1) receptor inhibitor, is widely...
5.
Xie J, Bruggeman A, De Nolf C, Vandendriessche C, Van Imschoot G, Van Wonterghem E, et al.
EMBO J
. 2023 Jul;
42(17):e111515.
PMID: 37427561
Accumulating evidence indicates that gut microbiota dysbiosis is associated with increased blood-brain barrier (BBB) permeability and contributes to Alzheimer's disease (AD) pathogenesis. In contrast, the influence of gut microbiota on...
6.
Claeys W, Van Hoecke L, Lernout H, De Nolf C, Van Imschoot G, Van Wonterghem E, et al.
J Neuroinflammation
. 2023 May;
20(1):130.
PMID: 37248507
Hepatic encephalopathy (HE) is a common complication of liver cirrhosis, associated with high morbidity and mortality, for which no brain-targeted therapies exist at present. The interplay between hyperammonemia and inflammation...
7.
Xie J, Cools L, Van Imschoot G, Van Wonterghem E, Pauwels M, Vlaeminck I, et al.
J Extracell Vesicles
. 2023 Feb;
12(2):e12306.
PMID: 36792546
The gut microbiota represents a diverse and dynamic population of microorganisms that can influence the health of the host. Increasing evidence supports the role of the gut microbiota as a...
8.
Van Wonterghem E, Van Hoecke L, Van Imschoot G, Verhaege D, Burgelman M, Vandenbroucke R
J Vis Exp
. 2023 Jan;
(190).
PMID: 36591985
The choroid plexus (CP), a highly vascularized structure protruding into the ventricles of the brain, is one of the most understudied tissues in neuroscience. As it is becoming increasingly clear...
9.
Pauwels M, Xie J, Ceroi A, Balusu S, Castelein J, Van Wonterghem E, et al.
Biomaterials
. 2022 Oct;
290:121830.
PMID: 36302306
The brain is protected against invading organisms and other unwanted substances by tightly regulated barriers. However, these central nervous system (CNS) barriers impede the delivery of drugs into the brain...
10.
Claeys W, Van Hoecke L, Geerts A, Van Vlierberghe H, Lefere S, Van Imschoot G, et al.
Sci Rep
. 2022 Oct;
12(1):17558.
PMID: 36266427
Hepatic encephalopathy (HE) is a common complication of chronic liver disease, characterized by an altered mental state and hyperammonemia. Insight into the brain pathophysiology of HE is limited due to...