Wootae Kim
Overview
Explore the profile of Wootae Kim including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
707
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Recent Articles
1.
Zhao F, Cai C, Gao H, Moon J, Christyani G, Qin S, et al.
Nucleic Acids Res
. 2025 Mar;
53(5).
PMID: 40052822
The TopBP1-ATR axis is critical for maintaining genomic stability during DNA replication stress, yet the precise regulation of TopBP1 in replication stress responses remains poorly understood. In this study, we...
2.
He L, Moon J, Cai C, Hao Y, Lee H, Kim W, et al.
DNA Repair (Amst)
. 2025 Jan;
146:103811.
PMID: 39848026
Proper chromatin remodeling is crucial for many cellular physiological processes, including the repair of DNA double-strand break (DSB). While the mechanism of DSB repair is well understood, the connection between...
3.
Diskul-Na-Ayudthaya P, Bae S, Bae Y, Van N, Kim W, Ryu S
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39409926
Early detection and surgical excision of tumors have helped improve the survival rate of patients with breast cancer. However, patients with metastatic cancer typically have a poor prognosis. In this...
4.
Huang M, Qin S, Gao H, Kim W, Xie F, Yin P, et al.
Cells
. 2024 Oct;
13(19.
PMID: 39404386
Most patients with metastatic prostate cancer eventually develop resistance to primary androgen deprivation therapy. To identify predictive biomarker for Abiraterone acetate/prednisone resistance, we screened alternative splice variants between responders and...
5.
Christyani G, Carswell M, Qin S, Kim W
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38256274
Cancer stands as the leading global cause of mortality, with rare cancer comprising 230 distinct subtypes characterized by infrequent incidence. Despite the inherent challenges in addressing the diagnosis and treatment...
6.
Qu Y, Qin S, Yang Z, Li Z, Liang Q, Long T, et al.
Biomed Pharmacother
. 2023 Nov;
169:115877.
PMID: 37951025
DNA repair is a vital mechanism in cells that protects against DNA damage caused by internal and external factors. It involves a network of signaling pathways that monitor and transmit...
7.
Qin S, Kitty I, Hao Y, Zhao F, Kim W
Int J Mol Sci
. 2023 Jun;
24(12).
PMID: 37373360
DNA double-strand breaks (DSBs) are the most lethal DNA damages which lead to severe genome instability. Phosphorylation is one of the most important protein post-translation modifications involved in DSBs repair...
8.
Moon J, Kitty I, Renata K, Qin S, Zhao F, Kim W
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36902170
DNA damage is a double-edged sword in cancer cells. On the one hand, DNA damage exacerbates gene mutation frequency and cancer risk. Mutations in key DNA repair genes, such as...
9.
Huang J, Wu C, Kloeber J, Gao H, Gao M, Zhu Q, et al.
Mol Cell
. 2023 Feb;
83(7):1043-1060.e10.
PMID: 36854302
Repair of DNA double-strand breaks (DSBs) elicits three-dimensional (3D) chromatin topological changes. A recent finding reveals that 53BP1 assembles into a 3D chromatin topology pattern around DSBs. How this formation...
10.
Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, et al.
Nat Commun
. 2022 Nov;
13(1):7190.
PMID: 36418323
No abstract available.