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Woojun D Park

Explore the profile of Woojun D Park including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 107
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Recent Articles
1.
Morelli E, Fulciniti M, Samur M, Ribeiro C, Wert-Lamas L, Henninger J, et al.
Blood . 2022 Sep; 141(4):391-405. PMID: 36126301
Long noncoding RNAs (lncRNAs) can drive tumorigenesis and are susceptible to therapeutic intervention. Here, we used a large-scale CRISPR interference viability screen to interrogate cell-growth dependency to lncRNA genes in...
2.
Perez M, Sias-Garcia O, Daramola A, Wei H, Terrell M, Rashid R, et al.
Blood Adv . 2021 Sep; 5(23):4864-4876. PMID: 34543389
Somatic mutations are rare in pediatric acute myeloid leukemia (pAML), indicating that alternate strategies are needed to identify targetable dependencies. We performed the first enhancer mapping of pAML in 22...
3.
Sheppard H, DallAgnese A, Park W, Shamim M, Dubrulle J, Johnson H, et al.
Cell Rep Med . 2021 Feb; 2(1):100188. PMID: 33521702
Chordomas are rare spinal tumors addicted to expression of the developmental transcription factor brachyury. In chordomas, brachyury is super-enhancer associated and preferentially downregulated by pharmacologic transcriptional CDK inhibition, leading to...
4.
Kakeshpour T, Tamang T, Park W, Manohar M, Yang J, Hirschi K, et al.
Biotechniques . 2020 Jan; 68(4):214-218. PMID: 31939314
Artificial miRNA technology enables the generation of siRNAs to regulate the expression of targeted genes. However, the application of siRNAs to alter gene expression is challenging due to their instability...
5.
Olson C, Liang Y, Leggett A, Park W, Li L, Mills C, et al.
Cell Chem Biol . 2019 Mar; 26(6):792-803.e10. PMID: 30905681
Cyclin-dependent kinase 7 (CDK7) regulates both cell cycle and transcription, but its precise role remains elusive. We previously described THZ1, a CDK7 inhibitor, which dramatically inhibits superenhancer-associated gene expression. However,...
6.
Zheng J, He C, Qin Y, Lin G, Park W, Sun M, et al.
Plant J . 2018 Oct; 97(3):530-542. PMID: 30375131
Epicuticular waxes provide a hydrophobic barrier that protects land plants from environmental stresses. To elucidate the molecular functions of maize glossy mutants that reduce the accumulation of epicuticular waxes, eight...