Woo Suk Ahn
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Explore the profile of Woo Suk Ahn including associated specialties, affiliations and a list of published articles.
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10
Citations
514
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Recent Articles
1.
Xu P, Qiao K, Ahn W, Stephanopoulos G
Proc Natl Acad Sci U S A
. 2016 Sep;
113(39):10848-53.
PMID: 27621436
Harnessing lipogenic pathways and rewiring acyl-CoA and acyl-ACP (acyl carrier protein) metabolism in Yarrowia lipolytica hold great potential for cost-efficient production of diesel, gasoline-like fuels, and oleochemicals. Here we assessed...
2.
Ahn W, Crown S, Antoniewicz M
Metab Eng
. 2016 May;
37:72-78.
PMID: 27174718
The pentose phosphate pathway (PPP) is a fundamental component of cellular metabolism. It provides precursors for the biosynthesis of nucleotides and contributes to the production of reducing power in the...
3.
Wasylenko T, Ahn W, Stephanopoulos G
Metab Eng
. 2015 Mar;
30:27-39.
PMID: 25747307
Oleaginous microbes represent an attractive means of converting a diverse range of feedstocks into oils that can be transesterified to biodiesel. However, the mechanism of lipid overproduction in these organisms...
4.
Zhang J, Ahn W, Gameiro P, Keibler M, Zhang Z, Stephanopoulos G
Methods Enzymol
. 2014 May;
542:369-89.
PMID: 24862276
Glutamine has recently emerged as a key substrate to support cancer cell proliferation, and the quantification of its metabolic flux is essential to understand the mechanisms by which this amino...
5.
Ahn W, Antoniewicz M
Metab Eng
. 2012 Nov;
15:34-47.
PMID: 23111062
We applied a parallel labeling strategy using two isotopic tracers, [1,2-(13)C]glucose and [U-(13)C]glutamine, to determine metabolic fluxes in Chinese hamster ovary (CHO) cells. CHO cells were grown in parallel cultures...
6.
Crown S, Ahn W, Antoniewicz M
BMC Syst Biol
. 2012 May;
6:43.
PMID: 22591686
Background: ¹³C-Metabolic flux analysis (¹³C-MFA) is a standard technique to probe cellular metabolism and elucidate in vivo metabolic fluxes. 13C-Tracer selection is an important step in conducting ¹³C-MFA, however, current...
7.
Ahn W, Antoniewicz M
Biotechnol J
. 2011 Nov;
7(1):61-74.
PMID: 22102428
Chinese hamster ovary (CHO) cells are the most widely used mammalian cell line for biopharmaceutical production, with a total global market approaching $100 billion per year. In the pharmaceutical industry...
8.
Ahn W, Antoniewicz M
Metab Eng
. 2011 Aug;
13(5):598-609.
PMID: 21821143
Chinese hamster ovary (CHO) cells are the main platform for production of biotherapeutics in the biopharmaceutical industry. However, relatively little is known about the metabolism of CHO cells in cell...
9.
Crown S, Indurthi D, Ahn W, Choi J, Papoutsakis E, Antoniewicz M
Biotechnol J
. 2011 Mar;
6(3):300-5.
PMID: 21370473
Solventogenic clostridia are an important class of microorganisms that can produce various biofuels. One of the bottlenecks in engineering clostridia stems from the fact that central metabolic pathways remain poorly...
10.
Ahn W, Jeon J, Jeong Y, Lee S, Yoon S
Biotechnol Bioeng
. 2008 Nov;
101(6):1234-44.
PMID: 18980186
To investigate the effect of culture temperature on erythropoietin (EPO) production and glycosylation in recombinant Chinese hamster ovary (CHO) cells, we cultivated CHO cells using a perfusion bioreactor. Cells were...