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Wonryull Koh

Explore the profile of Wonryull Koh including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 95
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Recent Articles
1.
Yang B, Xu Y, Maxwell A, Koh W, Gong P, Zhang C
BMC Syst Biol . 2018 Dec; 12(Suppl 7):115. PMID: 30547796
Background: Reconstruction of gene regulatory networks (GRNs), also known as reverse engineering of GRNs, aims to infer the potential regulation relationships between genes. With the development of biotechnology, such as...
2.
Blackwell K, Wallace L, Kim B, Oliveira R, Koh W
Methods Mol Biol . 2013 Jan; 964:61-75. PMID: 23296778
Dopamine binding to various dopamine receptors activates multiple intracellular signaling molecules, some of which interact with calcium activated signaling pathways. Many experiments measure agonist-stimulated elevations in signaling molecules using prolonged,...
3.
Koh W, Blackwell K
J Chem Phys . 2012 Oct; 137(15):154111. PMID: 23083152
The spatial direct method with gradient-based diffusion is an accelerated stochastic reaction-diffusion simulation algorithm that treats diffusive transfers between neighboring subvolumes based on concentration gradients. This recent method achieved a...
4.
Koh W, Blackwell K
J Chem Phys . 2011 Apr; 134(15):154103. PMID: 21513371
Stochastic simulation of reaction-diffusion systems enables the investigation of stochastic events arising from the small numbers and heterogeneous distribution of molecular species in biological cells. Stochastic variations in intracellular microdomains...
5.
Oliveira R, Terrin A, Benedetto G, Cannon R, Koh W, Kim M, et al.
PLoS One . 2010 Jul; 5(7):e11725. PMID: 20661441
Cyclic AMP (cAMP) and its main effector Protein Kinase A (PKA) are critical for several aspects of neuronal function including synaptic plasticity. Specificity of synaptic plasticity requires that cAMP activates...
6.
Koh W, McCormick B
IEEE Trans Med Imaging . 2009 Mar; 28(4):555-63. PMID: 19272992
Boundary surface approximation of 3-D neuroanatomical regions from sparse 2-D images (e.g., mouse brain olfactory bulb structures from a 2-D brain atlas) has proven to be difficult due to the...