Wondossen Sime
Overview
Explore the profile of Wondossen Sime including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
22
Citations
383
Followers
0
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Recent Articles
11.
Satapathy S, Topi G, Osman J, Hellman K, Ek F, Olsson R, et al.
Oncogenesis
. 2020 Aug;
9(8):74.
PMID: 32814764
Inflammation is an established risk factor for colorectal cancer. We and others have shown that colorectal cancer patients with elevated cysteinyl leukotriene receptor 2 (CysLTR) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) levels...
12.
Serrano S, Sime W, Abassi Y, Daams R, Massoumi R, Jemaa M
Sci Rep
. 2020 Jul;
10(1):11997.
PMID: 32686724
Neuroblastoma is the most common paediatric cancer type. Patients diagnosed with high-risk neuroblastoma have poor prognosis and occasionally tumours relapse. As a result, novel treatment strategies are needed for relapse...
13.
Sime W, Niu Q, Abassi Y, Masoumi K, Zarrizi R, Kohler J, et al.
Cell Death Dis
. 2018 Apr;
9(5):458.
PMID: 29686263
BRCA1-associated protein 1 (BAP1) is a nuclear deubiquitinating enzyme that is associated with multiprotein complexes that regulate key cellular pathways, including cell cycle, cellular differentiation, cell death, and the DNA...
14.
Masoumi K, Daams R, Sime W, Siino V, Ke H, Levander F, et al.
Mol Biol Cell
. 2016 Dec;
28(2):346-355.
PMID: 27903773
The Wnt signaling pathway is essential in regulating various cellular processes. Different mechanisms of inhibition for Wnt signaling have been proposed. Besides β-catenin degradation through the proteasome, nemo-like kinase (NLK)...
15.
Bellamkonda K, Sime W, Sjolander A
Mol Carcinog
. 2014 Aug;
54(11):1315-27.
PMID: 25154976
The role of inflammatory lipid-mediators in tumor progression is well recognized in colorectal cancer; however, if this includes promotion of cancer-initiating cells remains unclear. We show that the inflammatory lipid-mediators...
16.
Savari S, Liu M, Zhang Y, Sime W, Sjolander A
PLoS One
. 2013 Sep;
8(9):e73466.
PMID: 24039952
The expression of the inflammatory G-protein coupled receptor CysLT1R has been shown to be upregulated in colon cancer patients and associated with poor prognosis. The present study investigated the correlation...
17.
Zhang Y, Sime W, Juhas M, Sjolander A
Eur J Cancer
. 2013 Jul;
49(15):3320-34.
PMID: 23810249
Tumour-associated macrophages (TAMs) of the M2 phenotype are present in the stroma of many tumours and are frequently associated with the progression of several types of cancer. We investigated the...
18.
Parhamifar L, Sime W, Yudina Y, Vilhardt F, Morgelin M, Sjolander A
PLoS One
. 2011 Jan;
5(12):e14439.
PMID: 21203429
Background: Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly...
19.
Sime W, Lunderius-Andersson C, Enoksson M, Rousselle P, Tryggvason K, Nilsson G, et al.
J Immunol
. 2009 Sep;
183(7):4657-65.
PMID: 19752234
Mast cells (MCs) are multifunctional effectors of the immune system that are distributed in many tissues, often in close association with the basement membrane of blood vessels, epithelium and nerves....
20.
Mei H, Yoshida T, Sime W, Hiepe F, Thiele K, Manz R, et al.
Blood
. 2008 Nov;
113(11):2461-9.
PMID: 18987362
Providing humoral immunity, antibody-secreting plasma cells and their immediate precursors, the plasmablasts, are generated in systemic and mucosal immune reactions. Despite their key role in maintaining immunity and immunopathology, little...