Wolfram T Knoefel
Overview
Explore the profile of Wolfram T Knoefel including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
132
Citations
2353
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Schneider A, Koppe C, Crouchet E, Papargyriou A, Singer M, Buttner V, et al.
Nat Commun
. 2025 Feb;
16(1):1765.
PMID: 39971907
KRAS-dependent acinar-to-ductal metaplasia (ADM) is a fundamental step in the development of pancreatic ductal adenocarcinoma (PDAC), but the involvement of cell death pathways remains unclear. Here, we show that key...
2.
Cieslik S, Zafra A, Driemel C, Sudarsanam M, Cieslik J, Flugen G, et al.
J Exp Clin Cancer Res
. 2025 Jan;
44(1):9.
PMID: 39773651
Background: Circulating tumour cells (CTCs) and tumour-derived extracellular vesicles (tdEVs) have great potential for monitoring therapy response and early detection of tumour relapse, facilitating personalized adjuvant therapeutic strategies. However, their...
3.
Jordens M, Oswald H, Heinrichs L, Gassmann N, Wittig L, Luedde T, et al.
World J Surg Oncol
. 2025 Jan;
23(1):9.
PMID: 39762956
Background: Hepatocellular Carcinoma (HCC) and cholangiocellular adenocarcinoma (CCA) are the most common primary liver tumors representing a major global health burden. In early disease stages, tumor resection may provide long-term...
4.
Bone mineral density as a prognostic marker in patients with biliary tract cancer undergoing surgery
Heinrichs L, Fluegen G, Loosen S, Loberg C, Wittig L, Quaas A, et al.
BJC Rep
. 2024 Sep;
2(1):72.
PMID: 39323978
Background: Biliary tract cancer (BTC) is one of the most aggressive malignancies and surgery represents the only curative treatment approach. However, even in patients with complete tumor resection 5-year survival...
5.
Vaghiri S, Prassas D, Kalmuk S, Buehler G, Lehwald-Tywuschik N, Knoefel W, et al.
Minerva Surg
. 2024 Jul;
79(4):419-429.
PMID: 38953755
Background: The surgical management of perihilar carcinoma (pCCA) is still subject of ongoing debate. To provide more clarity, this study was conducted to evaluate outcomes related to the side and...
6.
Kandler J, Essing T, Scholer D, Flugen G, Knoefel W, Roderburg C, et al.
PLoS One
. 2024 Jan;
19(1):e0297265.
PMID: 38261581
Background/aims: While surgery remains a standard treatment for primary esophageal motility disorders (PEMDs), per-oral endoscopic myotomy (POEM) has recently evolved as an alternative. Systematic data on current trends of invasive...
7.
Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis
Stoecklein N, Fluegen G, Guglielmi R, Neves R, Hackert T, Birgin E, et al.
Mol Cancer
. 2023 Nov;
22(1):181.
PMID: 37957606
The limited sensitivity of circulating tumor cell (CTC) detection in pancreatic adenocarcinoma (PDAC) stems from their extremely low concentration in the whole circulating blood, necessitating enhanced detection methodologies. This study...
8.
Issels R, Boeck S, Pelzer U, Mansmann U, Ghadjar P, Lindner L, et al.
Eur J Cancer
. 2023 Jan;
181:155-165.
PMID: 36657324
Background: Regional hyperthermia (RHT) with cisplatin added to gemcitabine showed efficacy in gemcitabine-pre-treated patients with advanced pancreatic ductal adenocarcinoma. We conducted a randomised clinical trial to investigate RHT with cisplatin...
9.
Loosen S, Halpaap J, Labuhn S, Bednarsch J, Alizai P, Roeth A, et al.
Cancers (Basel)
. 2022 Sep;
14(18).
PMID: 36139589
Background: Tumor resection represents the only potentially curative therapy for patients with biliary tract cancer. Nevertheless, disease recurrence is observed in about 50% of patients, leading to a 5-years survival...
10.
Jordens M, Wittig L, Loberg C, Heinrichs L, Keitel V, Schulze-Hagen M, et al.
Biomedicines
. 2022 Jul;
10(7).
PMID: 35884968
Background: Cholangiocellular adenocarcinoma (CCA) is a rare and aggressive malignancy originating from the bile ducts. Its general prognosis is poor as therapeutic options are limited. Many patients present with advanced...