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Wolfram Horz

Explore the profile of Wolfram Horz including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 879
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Recent Articles
1.
Wippo C, Krstulovic B, Ertel F, Musladin S, Blaschke D, Sturzl S, et al.
Mol Cell Biol . 2009 Mar; 29(11):2960-81. PMID: 19307305
We showed previously that the strong PHO5 promoter is less dependent on chromatin cofactors than the weaker coregulated PHO8 promoter. In this study we asked if chromatin remodeling at the...
2.
Barbaric S, Luckenbach T, Schmid A, Blaschke D, Horz W, Korber P
J Biol Chem . 2007 Jul; 282(38):27610-21. PMID: 17631505
Induction of the yeast PHO5 and PHO8 genes leads to a prominent chromatin transition at their promoter regions as a prerequisite for transcription activation. Although induction of PHO8 is strictly...
3.
Korber P, Barbaric S, Luckenbach T, Schmid A, Schermer U, Blaschke D, et al.
J Biol Chem . 2006 Jan; 281(9):5539-45. PMID: 16407267
Eukaryotic gene expression starts off from a largely obstructive chromatin substrate that has to be rendered accessible by regulated mechanisms of chromatin remodeling. The yeast PHO5 promoter is a well...
4.
Hertel C, Langst G, Horz W, Korber P
Mol Cell Biol . 2005 Nov; 25(24):10755-67. PMID: 16314501
The coregulated PHO5 and PHO8 genes in Saccharomyces cerevisiae provide typical examples for the role of chromatin in promoter regulation. It has been a long-standing question why the cofactors Snf2...
5.
Schermer U, Korber P, Horz W
Mol Cell . 2005 Jul; 19(2):279-85. PMID: 16039596
In yeast, remodeling of PHO5 promoter chromatin upon activation is accompanied by transient hyperacetylation and subsequent eviction of histones from the promoter in trans. In the course of rerepression, nucleosomes...
6.
Korber P, Luckenbach T, Blaschke D, Horz W
Mol Cell Biol . 2004 Dec; 24(24):10965-74. PMID: 15572697
The yeast PHO5 promoter is a model system for the role of chromatin in eukaryotic gene regulation. Four positioned nucleosomes in the repressed state give way to an extended DNase...
7.
Korber P, Horz W
J Biol Chem . 2004 Jun; 279(33):35113-20. PMID: 15192097
An extensive set of analyses of the yeast PHO5 gene, mostly performed in vivo, has made this gene a model for the role of chromatin structure in gene regulation. In...
8.
Korber P, Horz W
Cell . 2004 Apr; 117(1):5-7. PMID: 15066277
The recently isolated SWR1 complex catalyzes an ATP-dependent histone exchange with specificity for the histone variant H2A.Z. This provides a new theme in chromatin remodeling mechanisms and an explanation of...
9.
Reinke H, Horz W
Biochim Biophys Acta . 2004 Mar; 1677(1-3):24-9. PMID: 15020042
The 600-bp accessible region at the activated PHO5 promoter in S. cerevisiae has become a paradigm for hypersensitive sites. In this review, we summarize the various experimental strategies used to...
10.
Reinke H, Horz W
Mol Cell . 2003 Jun; 11(6):1599-607. PMID: 12820972
We have analyzed the histone modification status of the PHO5 promoter from yeast by the ChIP technology and have focused on changes occurring upon activation. Using various acetylation-specific antibodies, we...