Witold N Nowak
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Explore the profile of Witold N Nowak including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
336
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Recent Articles
1.
Chudy P, Kochan J, Wawro M, Nguyen P, Gorczyca M, Varanko A, et al.
Redox Biol
. 2024 Jul;
75:103247.
PMID: 39047636
Heme oxygenase-1 (HO-1, HMOX1) degrades heme protecting cells from heme-induced oxidative damage. Beyond its well-established cellular functions, heme has emerged as a stabilizer of G-quadruplexes. These secondary DNA structures interfere...
2.
Krzeptowski W, Chudy P, Sokolowski G, Zukowska M, Kusienicka A, Seretny A, et al.
Antioxidants (Basel)
. 2021 Jan;
10(1).
PMID: 33445471
G-quadruplexes (G4) are stacked nucleic acid structures that are stabilized by heme. In cells, they affect DNA replication and gene transcription. They are unwound by several helicases but the composition...
3.
Szade A, Szade K, Nowak W, Bukowska-Strakova K, Muchova L, Gonka M, et al.
EMBO Mol Med
. 2019 Nov;
11(12):e09571.
PMID: 31709729
Granulocyte colony-stimulating factor (G-CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin...
4.
Nowak W, Taha H, Markiewicz J, Kachamakova-Trojanowska N, Stepniewski J, Kloska D, et al.
Mediators Inflamm
. 2019 Aug;
2019:1868170.
PMID: 31396016
Myeloid angiogenic cells (MAC) derive from hematopoietic stem/progenitor cells (HSPCs) that are mobilized from the bone marrow. They home to sites of neovascularization and contribute to angiogenesis by production of...
5.
Gu W, Nowak W, Xie Y, Le Bras A, Hu Y, Deng J, et al.
Arterioscler Thromb Vasc Biol
. 2019 Jul;
39(10):2049-2066.
PMID: 31340667
Objective: Perivascular adipose tissue (PVAT) plays a vital role in maintaining vascular homeostasis. However, most studies ascribed the function of PVAT in vascular remodeling to adipokines secreted by the perivascular...
6.
Ni Z, Deng J, Potter C, Nowak W, Gu W, Zhang Z, et al.
Circ Res
. 2019 May;
125(2):223-241.
PMID: 31079549
Rationale: Transplantation-accelerated arteriosclerosis is one of the major challenges for long-term survival of patients with solid organ transplantation. Although stem/progenitor cells have been implicated to participate in this process, the...
7.
Kloska D, Kopacz A, Piechota-Polanczyk A, Nowak W, Dulak J, Jozkowicz A, et al.
Vascul Pharmacol
. 2018 Sep;
112:42-53.
PMID: 30170173
Aging is the most critical risk factor for the development of cardiovascular diseases and their complications. Therefore, the fine-tuning of cellular response to getting older is an essential target for...
8.
Gu W, Hong X, Le Bras A, Nowak W, Bhaloo S, Deng J, et al.
J Biol Chem
. 2018 Apr;
293(21):8089-8102.
PMID: 29643181
Tissue-engineered vascular grafts with long-term patency are greatly needed in the clinical settings, and smooth muscle cells (SMCs) are a critical graft component. Human mesenchymal stem cells (MSCs) are used...
9.
Xie Y, Potter C, Le Bras A, Nowak W, Gu W, Bhaloo S, et al.
Arterioscler Thromb Vasc Biol
. 2017 Sep;
37(11):2114-2127.
PMID: 28935755
Objective: Leptin is an adipokine initially thought to be a metabolic factor. Recent publications have shown its roles in inflammation and vascular disease, to which Sca-1 vascular progenitor cells within...
10.
Langrzyk A, Nowak W, Stepniewski J, Jazwa A, Florczyk-Soluch U, Jozkowicz A, et al.
Antioxid Redox Signal
. 2017 Sep;
29(2):169-190.
PMID: 28874054
Significance: The belief in the potency of stem cells has resulted in the medical applications of numerous cell types for organ repair, often with the low adherence to methodological stringency....