Wing Yip Tam
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Explore the profile of Wing Yip Tam including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
291
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Recent Articles
1.
Au N, Wu T, Chen X, Gao F, Li Y, Tam W, et al.
Neuron
. 2023 Dec;
111(24):3970-3987.e8.
PMID: 38086376
Peripheral nerves regenerate successfully; however, clinical outcome after injury is poor. We demonstrated that low-dose ionizing radiation (LDIR) promoted axon regeneration and function recovery after peripheral nerve injury (PNI). Genome-wide...
2.
Lui K, Huang Y, Sheikh M, Cheung K, Tam W, Sun K, et al.
J Cancer
. 2023 Nov;
14(17):3214-3226.
PMID: 37928422
Research on Rab-like protein 1A (RBEL1A) in the past two decades highlighted the oncogenic properties of this gene. Despite the emerging evidence, its importance in cancer biology was underrated. This...
3.
Au N, Chand R, Kumar G, Asthana P, Tam W, Tang K, et al.
Proc Natl Acad Sci U S A
. 2022 Oct;
119(44):e2121273119.
PMID: 36306327
Axon regeneration is an energy-demanding process that requires active mitochondrial transport. In contrast to the central nervous system (CNS), axonal mitochondrial transport in regenerating axons of the peripheral nervous system...
4.
Tam W, Wang X, Cheng A, Cheung K
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33673348
The cerebellum, the region of the brain primarily responsible for motor coordination and balance, also contributes to non-motor functions, such as cognition, speech, and language comprehension. Maldevelopment and dysfunction of...
5.
Tam W, Cheung K
J Mol Med (Berl)
. 2020 Jul;
98(9):1215-1234.
PMID: 32712726
The laboratory mouse is the most commonly used mammalian model for biomedical research. An enormous number of mouse models, such as gene knockout, knockin, and overexpression transgenic mice, have been...
6.
Lui N, Tam W, Gao C, Huang J, Wang C, Jiang L, et al.
Nat Commun
. 2017 May;
8:15079.
PMID: 28516904
In the cerebellar cortex, Purkinje cells (PCs) receive signals from different inputs through their extensively branched dendrites and serve as an integration centre. Defects in the dendritic development of PCs...
7.
Tam W, Au N, Ma C
Sci Rep
. 2016 Jun;
6:28580.
PMID: 27334934
Microglia are immune cells in the central nervous system (CNS) that contribute to primary innate immune responses. The morphology of microglia is closely associated with their functional activities. The majority...
8.
Tam W, Ma C
Sci Rep
. 2014 Dec;
4:7279.
PMID: 25452009
Microglia are generally considered the resident immune cells in the central nervous system (CNS) that regulate the primary events of neuroinflammatory responses. Microglia also play key roles in repair and...
9.
Tam W, Jiang L, Kwan K
Protoplasma
. 2014 Nov;
252(4):977-83.
PMID: 25422095
The lysosome is a membrane-bound organelle involved in the turnover of various intracellular and extracellular macromolecules. These are degraded by acidic hydrolases in the lumen of lysosome. The lysosomal membrane...
10.
Qiu L, Wu X, Chau J, Szeto I, Tam W, Guo Z, et al.
J Biol Chem
. 2008 May;
283(25):17175-83.
PMID: 18445591
Aldose reductase (AR) is implicated in the development of a number of diabetic complications, but the underlying mechanisms remain to be fully elucidated. We performed this study to determine whether...