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Wing-Yee Lo

Explore the profile of Wing-Yee Lo including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 2538
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Recent Articles
1.
Hoppe R, Winter S, Lo W, Michailidou K, Bolla M, Keeman R, et al.
NPJ Breast Cancer . 2025 Feb; 11(1):18. PMID: 39971965
The role of germline genetics in adjuvant aromatase inhibitor (AI) treatment efficacy in ER-positive breast cancer is poorly understood. We employed a two-stage candidate gene approach to examine associations between...
2.
Wichert K, Hoppe R, Ickstadt K, Behrens T, Winter S, Herold R, et al.
Eur J Epidemiol . 2023 Oct; 38(10):1053-1068. PMID: 37789226
Light-at-night triggers the decline of pineal gland melatonin biosynthesis and secretion and is an IARC-classified probable breast-cancer risk factor. We applied a large-scale molecular epidemiology approach to shed light on...
3.
Mueller S, Lai A, Valkovskaya M, Michailidou K, Bolla M, Wang Q, et al.
Genome Med . 2023 Jan; 15(1):7. PMID: 36703164
Background: Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes....
4.
Wang X, Chen H, Middha Kapoor P, Su Y, Bolla M, Dennis J, et al.
Cancer Res Commun . 2022 Oct; 2(4):211-219. PMID: 36303815
Background: Genome-wide association studies (GWAS) have identified more than 200 susceptibility loci for breast cancer, but these variants explain less than a fifth of the disease risk. Although gene-environment interactions...
5.
Aranza S, Roydhouse C, Mitchell C, Vissers J, Lo W, Grimmond S, et al.
Pathology . 2022 Jun; 55(4):568-571. PMID: 35691724
No abstract available.
6.
Wang X, Middha Kapoor P, Auer P, Dennis J, Dunning A, Wang Q, et al.
Sci Rep . 2022 Apr; 12(1):6199. PMID: 35418701
Use of menopausal hormone therapy (MHT) is associated with increased risk for breast cancer. However, the relevant mechanisms and its interaction with genetic variants are not fully understood. We conducted...
7.
Ahearn T, Zhang H, Michailidou K, Milne R, Bolla M, Dennis J, et al.
Breast Cancer Res . 2022 Jan; 24(1):2. PMID: 34983606
Background: Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate...
8.
Park H, Neumeyer S, Michailidou K, Bolla M, Wang Q, Dennis J, et al.
Br J Cancer . 2021 Aug; 125(8):1135-1145. PMID: 34341517
Background: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies, it is still equivocal whether smoking is causally related to breast cancer risk....
9.
Dorling L, Carvalho S, Allen J, Gonzalez-Neira A, Luccarini C, Wahlstrom C, et al.
N Engl J Med . 2021 Jan; 384(5):428-439. PMID: 33471991
Background: Genetic testing for breast cancer susceptibility is widely used, but for many genes, evidence of an association with breast cancer is weak, underlying risk estimates are imprecise, and reliable...
10.
Zhang H, Ahearn T, Lecarpentier J, Barnes D, Beesley J, Qi G, et al.
Nat Genet . 2020 May; 52(6):572-581. PMID: 32424353
Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls,...