Wim H de Jong
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Explore the profile of Wim H de Jong including associated specialties, affiliations and a list of published articles.
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70
Citations
2963
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Recent Articles
1.
Vermeire T, Hoet P, Ion R, Kratke R, Proykova A, Scott M, et al.
Regul Toxicol Pharmacol
. 2023 Dec;
146:105527.
PMID: 38056706
The Opinion of the Scientific Committee on Health, Environmental and Emerging Risks advises the European Commission on whether the uses of titanium dioxide in toys and toy materials can be...
2.
Minnema J, Vandebriel R, Boer K, Klerx W, de Jong W, Delmaar C
Small
. 2023 Feb;
19(21):e2207326.
PMID: 36828794
Physiologically-based kinetic (PBK) modeling is a valuable tool to understand the kinetics of nanoparticles (NPs) in vivo. However, estimating PBK parameters remains challenging and commonly requires animal studies. To develop...
3.
Jennen D, van Herwijnen M, Jetten M, Vandebriel R, Keizers P, Geertsma R, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361846
Usage of injectable dermal fillers applied for aesthetic purposes has extensively increased over the years. As such, the number of related adverse reactions has increased, including patients showing severe complications...
4.
de Jong W, Geertsma R, Borchard G
Drug Deliv Transl Res
. 2022 Jul;
12(9):2042-2047.
PMID: 35908133
Nanotechnologies enable great opportunities for the development and use of innovative (nano)medicines. As is common for scientific and technical developments, recognized safety evaluation methods for regulatory purposes are lagging behind....
5.
de Jong W, Jennen D, Keizers P, Hodemaekers H, Vermeulen J, Bakker F, et al.
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806280
Resorbable tissue fillers for aesthetic purposes can induce severe complications including product migration, late swelling, and inflammatory reactions. The relation between product characteristics and adverse effects is not well understood....
6.
Gosens I, Costa P, Olsson M, Stone V, Costa A, Brunelli A, et al.
NanoImpact
. 2022 May;
22:100313.
PMID: 35559970
Copper oxide nanoparticles (CuO NPs) have previously been shown to cause dose-dependent pulmonary toxicity following inhalation. Here, CuO NPs (10 nm), coated with polyethylenimine (PEI) or ascorbate (ASC) resulting in...
7.
Aslund A, Vandebriel R, Caputo F, de Jong W, Delmaar C, Hyldbakk A, et al.
Drug Deliv Transl Res
. 2022 Apr;
12(9):2114-2131.
PMID: 35426570
Biodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the encapsulating nanoparticle, and, thus, less dependent on the physicochemical properties of...
8.
Bernauer U, Bodin L, Chaudhry Q, Coenraads P, Dusinska M, Gaffet E, et al.
Regul Toxicol Pharmacol
. 2021 Sep;
126:105046.
PMID: 34560169
The Cosmetic Regulation (EC) No 1223/2009 specifically covers the risk of nanomaterials used in cosmetic products. If there are concerns regarding the safety of a nanomaterial, the European Commission refers...
9.
de Jong W, Panagiotakos D, Proykova A, Samaras T, Clemens M, de Jong D, et al.
Regul Toxicol Pharmacol
. 2021 Jul;
125:104982.
PMID: 34214611
The Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) was requested by the European Commission (EC) to provide a scientific opinion on the safety of breast implants in relation...
10.
de Jong W, Carraway J, Liu C, Fan C, Liu J, Turley A, et al.
Toxicol In Vitro
. 2020 Sep;
69:104995.
PMID: 32891721
The ISO 10993 standards on biocompatibility assessment of medical devices discourage the use of animal tests when reliable and validated in vitro methods are available. A round robin validation study...