Wilson S Colucci
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Explore the profile of Wilson S Colucci including associated specialties, affiliations and a list of published articles.
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113
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Recent Articles
11.
Ngo D, Sverdlov A, Karki S, Macartney-Coxson D, Stubbs R, Farb M, et al.
Am J Physiol Endocrinol Metab
. 2018 Dec;
316(2):E168-E177.
PMID: 30576243
Obesity, particularly visceral adiposity, has been linked to mitochondrial dysfunction and increased oxidative stress, which have been suggested as mechanisms of insulin resistance. The mechanism(s) behind this remains incompletely understood....
12.
Luptak I, Croteau D, Valentine C, Qin F, Siwik D, Remick D, et al.
Shock
. 2018 Aug;
52(1):52-60.
PMID: 30102640
Mice challenged with lipopolysaccharide develop cardiomyopathy in a sex and redox-dependent fashion. Here we extended these studies to the cecal ligation and puncture (CLP) model.We compared male and female FVB...
13.
Panagia M, Chen H, Croteau D, Chen Y, Ran C, Luptak I, et al.
Circ Cardiovasc Imaging
. 2018 Mar;
11(3):e007007.
PMID: 29555834
Background: Substrate utilization in tissues with high energetic requirements could play an important role in cardiometabolic disease. Current techniques to assess energetics are limited by high cost, low throughput, and...
14.
Luptak I, Sverdlov A, Panagia M, Qin F, Pimentel D, Croteau D, et al.
J Mol Cell Cardiol
. 2018 Feb;
116:106-114.
PMID: 29409987
Metabolic syndrome is a cluster of obesity-related metabolic abnormalities that lead to metabolic heart disease (MHD) with left ventricular pump dysfunction. Although MHD is thought to be associated with myocardial...
15.
Holubarsch C, Colucci W, Eha J
Am J Cardiovasc Drugs
. 2017 Oct;
18(1):25-36.
PMID: 29080984
Preparations from Crataegus (hawthorn) have a long history in the treatment of heart failure. WS 1442 is a dry extract from hawthorn leaves with flowers (4-6.6:1), extraction solvent of ethanol...
16.
Ho J, Rahban Y, Sandhu H, Hiremath P, Ayalon N, Qin F, et al.
Obesity (Silver Spring)
. 2017 Jul;
25(9):1516-1522.
PMID: 28737258
Objective: Metabolic syndrome (MetS) can lead to myocardial fibrosis, diastolic dysfunction, and eventual heart failure. This study evaluated alterations in myocardial microstructure in people with MetS by using a novel...
17.
Morse J, Huang J, Khona N, Miller E, Siwik D, Colucci W, et al.
Anesthesiology
. 2017 Apr;
126(6):1125-1138.
PMID: 28410273
Background: In surviving patients, sepsis-induced cardiomyopathy is spontaneously reversible. In the absence of any experimental data, it is generally thought that cardiac recovery in sepsis simply follows the remission of...
18.
Brown D, Perry J, Allen M, Sabbah H, Stauffer B, Shaikh S, et al.
Nat Rev Cardiol
. 2016 Dec;
14(4):238-250.
PMID: 28004807
Heart failure is a pressing worldwide public-health problem with millions of patients having worsening heart failure. Despite all the available therapies, the condition carries a very poor prognosis. Existing therapies...
19.
Xu X, Babo E, Qin F, Croteau D, Colucci W
IJC Metab Endocr
. 2016 Dec;
13:28-34.
PMID: 27942464
Background: Obesity and metabolic syndrome lead to the development of metabolic heart disease (MHD) that is characterized by left ventricular hypertrophy (LVH), diastolic dysfunction, and increased mitochondrial ROS. Caloric restriction...
20.
Hobai I, Aziz K, Buys E, Brouckaert P, Siwik D, Colucci W
Shock
. 2016 Jul;
46(6):713-722.
PMID: 27405063
In male mice, sepsis-induced cardiomyopathy develops as a result of dysregulation of myocardial calcium (Ca) handling, leading to depressed cellular Ca transients (ΔCai). ΔCai depression is partially due to inhibition...