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William U Shipley

Explore the profile of William U Shipley including associated specialties, affiliations and a list of published articles. Areas
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Articles 134
Citations 6721
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Recent Articles
1.
Dahl D, Rodgers J, Shipley W, Michaelson M, Wu C, Parker W, et al.
J Clin Oncol . 2024 Sep; 42(34):4095-4102. PMID: 39226514
Purpose: To investigate the use of radiation with radiosensitizing chemotherapy following repeated transurethral resection (trimodality therapy) as an alternative to radical cystectomy in T1 bladder cancer which has failed Bacillus...
2.
Coen J, Rodgers J, Saylor P, Lee C, Wu C, Parker W, et al.
Int J Radiat Oncol Biol Phys . 2024 Aug; 121(1):153-161. PMID: 39147209
Purpose: For bladder-sparing treatment of muscle-invasive bladder cancer, 5-fluorouracil/cisplatin with twice-daily radiation (FCT) or gemcitabine plus daily radiation (GD) are effective chemoradiation (CRT) regimens. This trial evaluated these regimens and...
3.
Rana Z, Kamran S, Shetty A, Sutera P, Song Y, Bazyar S, et al.
Eur Urol Oncol . 2024 Apr; 7(5):986-989. PMID: 38641541
Chemoradiation therapy (CRT) is a treatment for muscle-invasive bladder cancer (MIBC). Using a novel transcriptomic profiling panel, we validated prognostic immune biomarkers to CRT using 70 pretreatment tumor samples from...
4.
Mak K, Scannell Bryan M, Dignam J, Shipley W, Lin Y, Peters C, et al.
Eur Urol Focus . 2024 Feb; 10(2):271-278. PMID: 38307806
Background: Androgen deprivation therapy (ADT) has been associated with coronary heart disease and myocardial infarction (MI) in prostate cancer patients, but controversy persists regarding its effects on cardiovascular mortality (CVM)....
5.
Kamran S, Zhou Y, Otani K, Drumm M, Otani Y, Wu S, et al.
Clin Cancer Res . 2023 Oct; 29(24):5116-5127. PMID: 37870965
Purpose: There is an urgent need for biomarkers of radiation response in organ-sparing therapies. Bladder preservation with trimodality therapy (TMT), consisting of transurethral tumor resection followed by chemoradiation, is an...
6.
Dahl D, Karrison T, Michaelson M, Pham H, Wu C, Swanson G, et al.
Eur Urol Oncol . 2023 Jul; 7(1):83-90. PMID: 37442672
Background: Chemo-radiation is a well-established alternative to radical cystectomy in patients with muscle-invasive bladder cancer. Many patients due to age or medical comorbidity are unfit for either radical cystectomy, or...
7.
Nguyen P, Huang H, Spratt D, Davicioni E, Sandler H, Shipley W, et al.
Int J Radiat Oncol Biol Phys . 2023 Jan; 116(3):521-529. PMID: 36596347
Purpose: Decipher is a genomic classifier (GC) prospectively validated postprostatectomy. We validated the performance of the GC in pretreatment biopsy samples within the context of 3 randomized phase 3 high-risk...
8.
Magliocco A, Moughan J, Miyamoto D, Simko J, Shipley W, Gray P, et al.
JAMA Netw Open . 2022 Nov; 5(11):e2242378. PMID: 36383379
Importance: Bladder-preserving trimodality therapy can be an effective alternative to radical cystectomy for treatment of muscle-invasive bladder cancer (MIBC), but biomarkers are needed to guide optimal patient selection. The DNA...
9.
Jackson W, Tang M, Schipper M, Sandler H, Zumsteg Z, Efstathiou J, et al.
J Clin Oncol . 2022 Jun; 40(27):3172-3179. PMID: 35737923
Purpose: Metastasis-free survival (MFS), but not event-free survival, is a validated surrogate end point for overall survival (OS) in men treated for localized prostate cancer. It remains unknown if this...
10.
Jones C, Pugh S, Sandler H, Chetner M, Amin M, Bruner D, et al.
Int J Radiat Oncol Biol Phys . 2021 Sep; 112(2):294-303. PMID: 34481017
Purpose: For men with localized prostate cancer, NRG Oncology/Radiation Therapy Oncology Group (RTOG) 9408 demonstrated that adding short-term androgen deprivation therapy (ADT) to radiation therapy (RT) improved the primary endpoint...