William Tseng
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Explore the profile of William Tseng including associated specialties, affiliations and a list of published articles.
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10
Citations
260
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Recent Articles
1.
Gordon E, Chawla S, Tellez W, Younesi E, Thomas S, Chua-Alcala V, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765863
Background: This Phase 1/2 study is based on the hypothesis that immune checkpoint inhibitors are more effective when given earlier in the course of the disease for advanced soft tissue...
2.
Kuo B, Li C, Chen J, Shiung Y, Chu C, Lee C, et al.
J Clin Invest
. 2022 Aug;
132(15).
PMID: 35912861
Over the last 2 decades, omalizumab is the only anti-IgE antibody that has been approved for asthma and chronic spontaneous urticaria (CSU). Ligelizumab, a higher-affinity anti-IgE mAb and the only...
3.
Yang J, Hsu J, Park S, Lee S, Li J, Bai M, et al.
Nat Commun
. 2019 Sep;
10(1):4068.
PMID: 31492851
The aldehyde dehydrogenase (ALDH) family of metabolic enzymes converts aldehydes to carboxylates. Here, we find that the reductive consequence of ALDH7A1 activity, which generates NADH (nicotinamide adenine dinucleotide, reduced form)...
4.
Wang C, Wong W, Tsai H, Chen Y, Kuo B, Lynn S, et al.
N Engl J Med
. 2019 Apr;
380(16):1535-1545.
PMID: 30995373
Background: Administration of a single broadly neutralizing human immunodeficiency virus (HIV)-specific antibody to HIV-infected persons leads to the development of antibody-resistant virus in the absence of antiretroviral therapy (ART). It...
5.
Nassif N, Tseng W, Borges C, Chen P, Eisenberg B
F1000Res
. 2017 Jan;
5:2907.
PMID: 28105325
Liposarcoma is the most common soft tissue sarcoma. With its various subtypes, the natural history of this disease can vary significantly from a locally recurrent tumor to a highly malignant...
6.
Ikoma N, Torres K, Somaiah N, Hunt K, Cormier J, Tseng W, et al.
Ann Surg Oncol
. 2014 Oct;
22(4):1068-72.
PMID: 25354575
Background: Surgery is the primary treatment for all subtypes of retroperitoneal liposarcoma, but neoadjuvant therapy may be warranted in cases of dedifferentiated liposarcoma (DDLS), which has an increased risk of...
7.
Chang H, Tseng W, Cui J, Costenbader K, Ho I
Arthritis Res Ther
. 2014 Jan;
16(1):R14.
PMID: 24433447
Introduction: A C-to-T single nucleotide polymorphism (SNP) located at position 1858 of human protein tyrosine phosphatase, non-receptor type 22 (PTPN22) complementary DNA (cDNA) is associated with an increased risk of...
8.
Tsao H, Tai T, Tseng W, Chang H, Grenningloh R, Miaw S, et al.
Proc Natl Acad Sci U S A
. 2013 Sep;
110(39):15776-81.
PMID: 24019486
E26 transformation-specific sequence 1 (Ets-1), the prototype of the ETS family of transcription factors, is critical for the expression of IL-2 by murine Th cells; however, its mechanism of action...
9.
Chang H, Miaw S, Tseng W, Sun Y, Liu C, Tsao H, et al.
J Immunol
. 2013 Aug;
191(5):2134-43.
PMID: 23913970
PTPN22, a protein tyrosine phosphatase expressed mainly in hematopoietic cells, has been linked to many autoimmune diseases. A C-to-T single nucleotide polymorphism (SNP) at position 1858 of human PTPN22 cDNA...
10.
Tseng W, Leong X, Engleman E
J Vis Exp
. 2008 Nov;
(10):484.
PMID: 18989400
The traditional subcutaneous tumor model is less than ideal for studying colorectal cancer. Orthotopic mouse models of colorectal cancer, which feature cancer cells growing in their natural location, replicate human...