William R Stauffer
Overview
Explore the profile of William R Stauffer including associated specialties, affiliations and a list of published articles.
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28
Citations
742
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Recent Articles
1.
Gonzalez-Burgos G, Gonzalez Burgos G, Miyamae T, Nishihata Y, Krimer O, Wade K, et al.
J Neurophysiol
. 2024 Dec;
133(2):399-413.
PMID: 39740351
The primate dorsolateral prefrontal cortex (DLPFC) displays unique in vivo activity patterns, but how in vivo activity regulates DLPFC pyramidal neuron (PN) properties remains unclear. We assessed the effects of...
2.
Kerkhoff W, Stauffer W
Curr Biol
. 2024 Nov;
34(22):R1149-R1152.
PMID: 39561711
A new study has identified a novel direct-indirect circuit architecture connecting the striosome compartment of the striatum with midbrain dopamine neurons. This circuit has the potential to integrate limbic and...
3.
Gonzalez Burgos G, Miyamae T, Nishihata Y, Krimer O, Wade K, Fish K, et al.
bioRxiv
. 2024 Jun;
PMID: 38915638
Significance Statement: In schizophrenia, dorsolateral prefrontal cortex (DLPFC) pyramidal neurons (PNs) have both transcriptional and structural alterations that suggest they are hypoactive. PN hypoactivity is thought to produce synaptic alterations...
4.
Liang L, Zimmermann Rollin I, Alikaya A, Ho J, Santini T, Bostan A, et al.
J Neurosci Methods
. 2024 Apr;
407:110133.
PMID: 38588922
Background: High-precision neurosurgical targeting in nonhuman primates (NHPs) often requires presurgical anatomical mapping with noninvasive neuroimaging techniques (MRI, CT, PET), allowing for translation of individual anatomical coordinates to surgical stereotaxic...
5.
6.
Hong T, Stauffer W
Nat Neurosci
. 2023 Apr;
26(5):850-857.
PMID: 37095398
Economic deliberations are slow, effortful and intentional searches for solutions to difficult economic problems. Although such deliberations are critical for making sound decisions, the underlying reasoning strategies and neurobiological substrates...
7.
Xi Z, Ozturk B, Johnson M, Turunc S, Stauffer W, Byrne L
Mol Ther Methods Clin Dev
. 2022 May;
25():476-489.
PMID: 35615708
Gene therapy is a rapidly developing field, and adeno-associated viruses (AAVs) are a leading viral-vector candidate for therapeutic gene delivery. Newly engineered AAVs with improved abilities are now entering the...
8.
Lawler A, Ramamurthy E, Brown A, Shin N, Kim Y, Toong N, et al.
Elife
. 2022 May;
11.
PMID: 35576146
Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations within heterogeneous tissue. Available approaches for engineering-targeted technologies for new neuron...
9.
He J, Kleyman M, Chen J, Alikaya A, Rothenhoefer K, Ozturk B, et al.
Curr Biol
. 2021 Nov;
31(24):5473-5486.e6.
PMID: 34727523
Medium spiny neurons (MSNs) constitute the vast majority of striatal neurons and the principal interface between dopamine reward signals and functionally diverse cortico-basal ganglia circuits. Information processing in these circuits...
10.
Ozturk B, Johnson M, Kleyman M, Turunc S, He J, Jabalameli S, et al.
Elife
. 2021 Oct;
10.
PMID: 34664552
Background: Adeno-associated virus (AAV)-mediated gene therapies are rapidly advancing to the clinic, and AAV engineering has resulted in vectors with increased ability to deliver therapeutic genes. Although the choice of...