Kenneth N Fish
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Explore the profile of Kenneth N Fish including associated specialties, affiliations and a list of published articles.
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65
Citations
1802
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Recent Articles
1.
Buck S, Mabry S, Glausier J, Banks-Tibbs T, Ward C, Kozel J, et al.
Mol Psychiatry
. 2025 Jan;
PMID: 39875589
Age-related dopamine (DA) neuron loss is a primary feature of Parkinson's disease. However, whether similar biological processes occur during healthy aging, but to a lesser degree, remains unclear. We therefore...
2.
Dienel S, Wade K, Fish K, Lewis D
Biol Psychiatry
. 2025 Jan;
PMID: 39848397
Background: Certain cognitive processes require inhibition provided by the somatostatin (SST) class of gamma-aminobutyric acid (GABA) neurons in the dorsolateral prefrontal cortex (DLPFC). This inhibition onto pyramidal neuron dendrites depends...
3.
Gonzalez-Burgos G, Gonzalez Burgos G, Miyamae T, Nishihata Y, Krimer O, Wade K, et al.
J Neurophysiol
. 2024 Dec;
133(2):399-413.
PMID: 39740351
The primate dorsolateral prefrontal cortex (DLPFC) displays unique in vivo activity patterns, but how in vivo activity regulates DLPFC pyramidal neuron (PN) properties remains unclear. We assessed the effects of...
4.
Gonzalez Burgos G, Miyamae T, Nishihata Y, Krimer O, Wade K, Fish K, et al.
bioRxiv
. 2024 Jun;
PMID: 38915638
Significance Statement: In schizophrenia, dorsolateral prefrontal cortex (DLPFC) pyramidal neurons (PNs) have both transcriptional and structural alterations that suggest they are hypoactive. PN hypoactivity is thought to produce synaptic alterations...
5.
Buck S, Mabry S, Glausier J, Banks-Tibbs T, Ward C, Kozel J, et al.
bioRxiv
. 2024 Jun;
PMID: 38854057
Age-related dopamine (DA) neuron loss is a primary feature of Parkinson's disease. However, it remains unclear whether similar biological processes occur during healthy aging, albeit to a lesser degree. We...
6.
Ruff C, Juarez Anaya F, Dienel S, Rakymzhan A, Altamirano-Espinoza A, Couey J, et al.
Cell Rep
. 2024 Mar;
43(4):113970.
PMID: 38512868
To meet the high energy demands of brain function, cerebral blood flow (CBF) parallels changes in neuronal activity by a mechanism known as neurovascular coupling (NVC). However, which neurons play...
7.
Chung Y, Dienel S, Belch M, Fish K, Ermentrout G, Lewis D, et al.
Mol Psychiatry
. 2024 Jan;
29(5):1382-1391.
PMID: 38273110
Deficient gamma oscillations in prefrontal cortex (PFC) of individuals with schizophrenia appear to involve impaired inhibitory drive from parvalbumin-expressing interneurons (PVIs). Inhibitory drive from PVIs is regulated, in part, by...
8.
Schoonover K, Miller N, Fish K, Lewis D
Neurobiol Dis
. 2024 Jan;
191:106394.
PMID: 38176569
Background: Dorsolateral prefrontal cortex (DLPFC) dysfunction in schizophrenia appears to reflect alterations in layer 3 pyramidal neurons (L3PNs), including smaller cell bodies and lower expression of mitochondrial energy production genes....
9.
Buck S, Rubin S, Kunkhyen T, Treiber C, Xue X, Fenno L, et al.
bioRxiv
. 2023 Oct;
PMID: 37873436
Parkinson's disease (PD) targets some dopamine (DA) neurons more than others. Sex differences offer insights, with females more protected from DA neurodegeneration. The mammalian vesicular glutamate transporter VGLUT2 and ortholog...
10.
Dienel S, Dowling K, Barile Z, Bazmi H, Liu A, Vespoli J, et al.
JAMA Psychiatry
. 2023 Aug;
80(12):1235-1245.
PMID: 37647039
Importance: Individuals with schizophrenia (SZ) exhibit pronounced deficits in somatostatin (SST) messenger RNA (mRNA) levels in the dorsolateral prefrontal cortex (DLPFC). Molecularly distinct subtypes of SST neurons, located in the...