William Mattox
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Explore the profile of William Mattox including associated specialties, affiliations and a list of published articles.
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10
Citations
252
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Recent Articles
1.
Gerard A, Noblin S, Hashmi S, Bean A, Bergstrom K, Hurst C, et al.
J Genet Couns
. 2018 Aug;
PMID: 30121717
Genetic counseling is a rapidly expanding field, and the supply of certified genetic counselors is currently unable to keep up with job demand. Research is fairly limited regarding the awareness...
2.
Wang S, Wagner E, Mattox W
RNA Biol
. 2013 Jul;
10(8):1396-406.
PMID: 23880637
The SR family of proteins plays important regulatory roles in the control of alternative splicing in a wide range of organisms. These factors affect splicing through both positive and negative...
3.
Shen M, Mattox W
Nucleic Acids Res
. 2011 Sep;
40(1):428-37.
PMID: 21914724
SR proteins and related factors play widespread roles in alternative pre-mRNA splicing and are known to promote splice site recognition through their Arg-Ser-rich effector domains. However, binding of SR regulators...
4.
Lazareva A, Roman G, Mattox W, Hardin P, Dauwalder B
PLoS Genet
. 2007 Jan;
3(1):e16.
PMID: 17257054
Mating behavior in Drosophila depends critically on the sexual identity of specific regions in the brain, but several studies have identified courtship genes that express products only outside the nervous...
5.
Qi J, Su S, Mattox W
Mol Cell Biol
. 2006 Nov;
27(2):699-708.
PMID: 17101798
The activation of sex-specific alternative splice sites in the Drosophila melanogaster doublesex and fruitless pre-mRNAs has been well studied and depends on the serine-arginine-rich (SR) splicing factors Tra, Tra2, and...
6.
Qi J, Su S, McGuffin M, Mattox W
Nucleic Acids Res
. 2006 Nov;
34(21):6256-63.
PMID: 17098939
The splicing factor Transformer-2 (Tra2) is expressed almost ubiquitously in Drosophila adults, but participates in the tissue-specific regulation of splicing in several RNAs. In somatic tissues Tra2 participates in the...
7.
Xu D, Mattox W
Hum Mol Genet
. 2005 Dec;
15(2):329-36.
PMID: 16357104
Exonic splicing enhancers (ESEs) are sequences that facilitate recognition of splice sites and prevent exon-skipping. Because ESEs are often embedded within protein-coding sequences, alterations in them can also often be...
8.
Unni E, Su S, Zraly C, Mattox W
Genesis
. 2003 Nov;
37(2):76-83.
PMID: 14595843
Tra2 is a regulator of pre-mRNA splicing and a key component of the Drosophila somatic sex determination pathway. Functional orthologs of this protein are thought to perform nonsex-specific functions essential...
9.
Chandler D, Qi J, Mattox W
Mol Cell Biol
. 2003 Jul;
23(15):5174-85.
PMID: 12861004
The Drosophila melanogaster sex determination factor Tra2 positively regulates the splicing of both doublesex (dsx) and fruitless (fru) pre-mRNAs but negatively affects the splicing of the M1 intron in tra2...
10.
Dauwalder B, Tsujimoto S, Moss J, Mattox W
Genes Dev
. 2002 Nov;
16(22):2879-92.
PMID: 12435630
The Drosophila somatic sex-determination regulatory pathway has been well studied, but little is known about the target genes that it ultimately controls. In a differential screen for sex-specific transcripts expressed...