William M Holmes
Overview
Explore the profile of William M Holmes including associated specialties, affiliations and a list of published articles.
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51
Citations
737
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Recent Articles
1.
Paterson S, Vallatos A, Graff C, Holmes W, Holmes W
Magn Reson Imaging
. 2025 Feb;
119:110361.
PMID: 39971260
Purpose: mbASL relies on the use of a series of adiabatic radio-frequency pulses to label successive boli of blood water. As the sequence is a hybrid of pCASL and PASL,...
2.
Alghanimy A, Work L, Holmes W
Mult Scler Relat Disord
. 2024 Jan;
83:105456.
PMID: 38266608
Multiple sclerosis (MS) is a complex autoimmune disorder that affects the central nervous system, resulting in demyelination and an array of neurological manifestations. Recently, there has been significant scientific interest...
3.
Lopez Gonzalez R, Holmes W
J Magn Reson Imaging
. 2023 Oct;
60(1):375-376.
PMID: 37855664
No abstract available.
4.
Paterson S, Vallatos A, Rodgers J, Holmes W
Sci Rep
. 2023 May;
13(1):8684.
PMID: 37248398
Human African Trypanosomiasis (HAT) is a parasitic disease originating in sub-Saharan Africa. There is limited information about the changes in the blood brain barrier (BBB) during this infection. This study...
5.
Alghanimy A, Martin C, Gallagher L, Holmes W
PLoS One
. 2023 Mar;
18(3):e0282955.
PMID: 36920936
The glymphatic system is a low resistance pathway, by which cerebrospinal fluid enters the brain parenchyma along perivascular spaces via AQP4 channels. It is hypothesised that the resulting convective flow...
6.
Alshuhri M, Gallagher L, Work L, Holmes W
JCI Insight
. 2021 Apr;
6(10).
PMID: 33857020
The recently proposed glymphatic pathway for solute transport and waste clearance from the brain has been the focus of intense debate. By exploiting an isotopically enriched MRI tracer, H217O, we...
7.
Al-Mubarak H, Vallatos A, Holmes W
J Magn Reson
. 2021 Mar;
325:106929.
PMID: 33713991
Phase-contrast magnetic resonance velocimetry (PC-MRI) has been widely used to investigate flow properties in numerous systems. In a horizontal cylindrical pipe (3 mm diameter), we investigated the accuracy of PC-MRI...
8.
Thow L, MacDonald K, Holmes W, Muir K, Macrae I, Dewar D
Brain Neurosci Adv
. 2020 Mar;
2:2398212818794820.
PMID: 32166145
Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood. We hypothesised that hyperglycaemia at the time...
9.
Faller K, Leach J, Johnston P, Holmes W, Macrae I, Frenguelli B
Brain Neurosci Adv
. 2020 Mar;
1:2398212817717112.
PMID: 32166133
Background: Cerebral ischaemia results in a rapid and profound depletion of adenosine triphosphate (ATP), the energy currency of the cell. This depletion leads to disruption of cellular homeostasis and cell...
10.
Jayasekera G, Wilson K, Buist H, Woodward R, Uckan A, Hughes C, et al.
Pulm Circ
. 2020 Feb;
10(1):2045894019897513.
PMID: 32095230
Cardiac magnetic resonance-derived ventricular variables are predictive of mortality in pulmonary arterial hypertension. Rodent models which emphasize ventricular function, allowing serial monitoring, are needed to identify pathophysiological features and novel...