William E Jackson 3rd
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Explore the profile of William E Jackson 3rd including associated specialties, affiliations and a list of published articles.
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10
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104
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Recent Articles
1.
MacVittie T, Farese A, Parker G, Bennett A, Jackson 3rd W
Health Phys
. 2020 Oct;
119(5):559-587.
PMID: 33009295
The nonhuman primate, rhesus macaque, is a relevant animal model that has been used to determine the efficacy of medical countermeasures to mitigate major signs of morbidity and mortality of...
2.
MacVittie T, Farese A, Jackson 3rd W
Health Phys
. 2020 Sep;
119(5):527-558.
PMID: 32947486
A systematic review of relevant studies that determined the dose response relationship (DRR) for the hematopoietic (H) acute radiation syndrome (ARS) in the canine relative to radiation quality of mixed...
3.
Grace M, Singh V, Rhee J, Jackson 3rd W, Kao T, Whitnall M
J Radiat Res
. 2012 Jul;
53(6):840-53.
PMID: 22843381
The steroid androst-5-ene-3ß,17ß-diol (5-androstenediol, 5-AED) elevates circulating granulocytes and platelets in animals and humans, and enhances survival during the acute radiation syndrome (ARS) in mice and non-human primates. 5-AED promotes...
4.
Singh V, Shafran R, Inal C, Jackson 3rd W, Whitnall M
Immunopharmacol Immunotoxicol
. 2006 Jan;
27(4):521-34.
PMID: 16435574
5-Androstenediol (5-AED) is a natural circulating adrenocortical steroid hormone that interconverts in vivo with other members of the 5-androstene family of steroids: dehydroepiandrosterone and 5-androstenetriol. These steroids stimulate immune responses...
5.
Singh V, Shafran R, Jackson 3rd W, Seed T, Kumar K
Exp Mol Pathol
. 2006 Jan;
81(1):55-61.
PMID: 16426603
Tocols are a family of eight isomers consisting of four tocopherols and four tocotrienols that exist in four isomeric forms: alpha (alpha), beta (beta), gamma (gamma), and delta (delta). Recently,...
6.
Whitnall M, Villa V, Seed T, Benjack J, Miner V, Lewbart M, et al.
Immunopharmacol Immunotoxicol
. 2005 Apr;
27(1):15-32.
PMID: 15803857
We compared in vivo radioprotective efficacy of 5-androstenediol (5-AED) to that of ten other steroids: 17alpha-androstenediol, dehydroepiandrosterone, 5-androstenetriol (AET), 4-androstenedione (AND), testosterone, estradiol, fluasterone, 16alpha-bromoepiandrosterone, 16alpha-fluoro-androst-5-en-17alpha-ol (alpha-fluorohydrin, AFH), and 16alpha-fluoro-androst-5-en-17beta-ol...
7.
Grace M, McLeland C, Gagliardi S, Smith J, Jackson 3rd W, Blakely W
Clin Chem
. 2003 Aug;
49(9):1467-75.
PMID: 12928227
Background: High-throughput and forward-deployable biological dosimetry capabilities are required for tactical and medical decisions after radiologic events. We previously reported a quantitative reverse transcription (QRT)-PCR assay for human radiation-responsive gene...
8.
Whitnall M, Wilhelmsen C, McKinney L, Miner V, Seed T, Jackson 3rd W
Immunopharmacol Immunotoxicol
. 2003 Jan;
24(4):595-626.
PMID: 12510793
We previously showed that one subcutaneous (sc) injection of 5-androstene-3beta,17beta-diol (AED) stimulated the innate immune system in mice and prevented mortality due to hemopoietic suppression after whole-body ionizing irradiation with...
9.
Pendergrass Jr J, Srinivasan V, Kumar K, Jackson 3rd W, Seed T
J AOAC Int
. 2002 Jun;
85(3):551-4.
PMID: 12083246
A liquid chromatographic method using electrochemical detection is presented for measuring the thiol WR-1065 12-(3-aminopropylamino) ethanethiol] and its symmetrical disulfide WR-33278 [NH2(CH2)3NHCH2CH2S]2. WR- 1065 is the active, radioprotective drug derived...
10.
Knudson G, Elliott T, Brook I, Shoemaker M, Pastel R, Lowy R, et al.
Mil Med
. 2002 Mar;
167(2 Suppl):95-7.
PMID: 11873528
The Armed Forces Radiobiological Research Institute (AFRRI) has developed a research program to determine the major health risks from exposure to ionizing radiation in combination with biological and chemical warfare...