William E Delaney Iv
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Explore the profile of William E Delaney Iv including associated specialties, affiliations and a list of published articles.
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5
Citations
113
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Recent Articles
1.
Gorsuch C, Nemec P, Yu M, Xu S, Han D, Smith J, et al.
Mol Ther
. 2022 May;
30(9):2909-2922.
PMID: 35581938
Persistence of chronic hepatitis B (CHB) is attributed to maintenance of the intrahepatic pool of the viral covalently closed circular DNA (cccDNA), which serves as the transcriptional template for all...
2.
Burdette D, Lazerwith S, Yang J, Chan H, Delaney Iv W, Fletcher S, et al.
PLoS One
. 2022 Apr;
17(4):e0262516.
PMID: 35363817
Nucleos(t)ide analogs are standard-of-care for the treatment of chronic hepatitis B and can effectively reduce hepatitis B virus (HBV) replication but rarely leads to cure. Nucleos(t)ide analogs do not directly...
3.
Birkus G, Snyder C, Jordan R, Kobayashi T, Dick R, Puscau V, et al.
Antiviral Res
. 2019 Jun;
169:104538.
PMID: 31226346
We describe here the anti-HBV activity of natural and synthetic retinoids in primary human hepatocytes (PHHs). The most potent compounds inhibited HBsAg, HBeAg, viral RNA and DNA production by HBV...
4.
Niu C, Livingston C, Li L, Beran R, Daffis S, Ramakrishnan D, et al.
PLoS One
. 2017 Jan;
12(1):e0169648.
PMID: 28095508
The structural maintenance of chromosome 5/6 complex (Smc5/6) is a restriction factor that represses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing HBV X protein (HBx), which...
5.
Chan K, Robinson M, Yang H, Cornew S, Delaney Iv W
Antiviral Res
. 2013 Feb;
98(1):85-92.
PMID: 23376631
The development of JFH1 based intergenotypic recombinants that exploit the unique replication characteristics of JFH1 has made it possible to study infectious hepatitis C virus (HCV) encoding the structural genes...