William David Arnold
Overview
Explore the profile of William David Arnold including associated specialties, affiliations and a list of published articles.
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10
Citations
53
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Recent Articles
1.
Suetterlin K, Law S, Arnold W
Front Neurol
. 2025 Jan;
15():1507485.
PMID: 39777323
In Periodic Paralysis (PP), a rare inherited condition caused by mutation in skeletal muscle ion channels, the phenotype changes with age, transitioning from the episodic attacks of weakness that give...
2.
Gronnebaek T, Haahr-Lillevang H, Skov M, Kelly K, Kerr N, Viteri J, et al.
Ann Clin Transl Neurol
. 2024 Dec;
12(2):320-331.
PMID: 39670429
Objective: Charcot-Marie Tooth (CMT) is a hereditary neuropathy characterized by muscle weakness and fatigue with no approved therapies. Preclinical studies implicate neuromuscular junction (NMJ) transmission deficits in muscle dysfunction in...
3.
Kerr N, Mossman C, Chou C, Bunten J, Kelty T, Childs T, et al.
J Appl Physiol (1985)
. 2024 Jul;
137(3):512-526.
PMID: 38961821
Alzheimer's disease (AD) is the fifth leading cause of death in older adults, and treatment options are severely lacking. Recent findings demonstrate a strong relationship between skeletal muscle and cognitive...
4.
Dashtmian A, Darvishi F, Arnold W
Cells
. 2024 Jun;
13(11.
PMID: 38891059
Amyotrophic Lateral Sclerosis (ALS) is a group of sporadic and genetic neurodegenerative disorders that result in losses of upper and lower motor neurons. Treatment of ALS is limited, and survival...
5.
Ketabforoush A, Wang M, Smith C, Arnold W, Nichols N
J Vis Exp
. 2024 May;
(206).
PMID: 38709037
Loss of ventilatory muscle function is a consequence of motor neuron injury and neurodegeneration (e.g., cervical spinal cord injury and amyotrophic lateral sclerosis, respectively). Phrenic motor neurons are the final...
6.
Differential impact on motor unit characteristics across severities of adult spinal muscular atrophy
Kelly K, Mizell J, Bigdeli L, Paul S, Tellez M, Bartlett A, et al.
Ann Clin Transl Neurol
. 2023 Sep;
10(12):2208-2222.
PMID: 37735861
Objective: To test the hypotheses that decomposition electromyography (dEMG) motor unit action potential (MUAP) amplitude and firing rate are altered in SMA; dEMG parameters are associated with strength and function;...
7.
Moore J, Wier C, Lemmerman L, Ortega-Pineda L, Dodd D, Lawrence W, et al.
Adv Biosyst
. 2020 Sep;
4(11):e2000157.
PMID: 32939985
While gene and cell therapies have emerged as promising treatment strategies for various neurological conditions, heavy reliance on viral vectors can hamper widespread clinical implementation. Here, the use of tissue...
8.
Sahenk Z, Yalvac M, Amornvit J, Arnold W, Chen L, Shontz K, et al.
Brain Behav
. 2018 Sep;
8(10):e01118.
PMID: 30239155
Introduction: Classic Charcot-Marie-Tooth (CMT) neuropathies including those with Schwann cell genetic defects exhibit a length-dependent process affecting the distal axon. Energy deprivation in the distal axon has been the proposed...
9.
Yalvac M, Arnold W, Hussain S, Braganza C, Shontz K, Clark K, et al.
Mol Ther
. 2014 Apr;
22(7):1353-1363.
PMID: 24762627
The spontaneous autoimmune peripheral polyneuropathy (SAPP) model in B7-2 knockout nonobese diabetic mice mimics a progressive and unremitting course of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). In this study, bone marrow-derived...
10.
Collins M, Arnold W, Kissel J
Neurol Clin
. 2013 May;
31(2):557-95.
PMID: 23642724
Vasculitic neuropathy can occur as an isolated entity (nonsystemic vasculitic neuropathy) but more commonly evolves in the setting of primary systemic vasculitides or secondary vasculitides related to infections, drugs, or...