William Breuer
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Explore the profile of William Breuer including associated specialties, affiliations and a list of published articles.
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30
Citations
1226
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Recent Articles
1.
Ramachandran R, Nandi I, Haritan N, Zlotkin-Rivkin E, Keren Y, Danieli T, et al.
Gut Microbes
. 2022 Oct;
14(1):2130657.
PMID: 36219160
Enteropathogenic are bacterial pathogens that colonize the gut and cause severe diarrhea in humans. Upon intimate attachment to the intestinal epithelium, these pathogens translocate via a type III secretion system...
2.
Kassa E, Zlotkin-Rivkin E, Friedman G, Ramachandran R, Melamed-Book N, Weiss A, et al.
PLoS Pathog
. 2019 Jun;
15(6):e1007851.
PMID: 31242273
Enteropathogenic E. coli (EPEC) is an extracellular diarrheagenic human pathogen which infects the apical plasma membrane of the small intestinal enterocytes. EPEC utilizes a type III secretion system to translocate...
3.
Radzinski M, Fassler R, Yogev O, Breuer W, Shai N, Gutin J, et al.
Elife
. 2018 Jun;
7.
PMID: 29869985
Cellular redox status affects diverse cellular functions, including proliferation, protein homeostasis, and aging. Thus, individual differences in redox status can give rise to distinct sub-populations even among cells with identical...
4.
Shiber A, Breuer W, Ravid T
Prion
. 2014 Dec;
8(3):276-84.
PMID: 25482598
The sequestration of misfolded proteins into aggregates is an integral pathway of the protein quality control network that becomes particularly prominent during proteotoxic stress and in various pathologies. Methods for...
5.
Shiber A, Breuer W, Brandeis M, Ravid T
Mol Biol Cell
. 2013 May;
24(13):2076-87.
PMID: 23637465
Ubiquitin accumulation in amyloid plaques is a pathological marker observed in the vast majority of neurodegenerative diseases, yet ubiquitin function in these inclusions is controversial. It has been suggested that...
6.
Sohn Y, Ghoti H, Breuer W, Rachmilewitz E, Attar S, Weiss G, et al.
Haematologica
. 2011 Dec;
97(5):670-8.
PMID: 22180428
Background: In transfusional siderosis, the iron binding capacity of plasma transferrin is often surpassed, with concomitant generation of non-transferrin-bound iron. Although implicated in tissue siderosis, non-transferrin-bound iron modes of cell...
7.
Breuer W, Ghoti H, Shattat A, Goldfarb A, Koren A, Levin C, et al.
Am J Hematol
. 2011 Nov;
87(1):55-61.
PMID: 22125177
Non-transferrin bound iron (NTBI) is commonly detected in patients with systemic iron overload whose serum iron-binding capacity has been surpassed. It has been perceived as an indicator of iron overload,...
8.
Sohn Y, Mitterstiller A, Breuer W, Weiss G, Cabantchik Z
Br J Pharmacol
. 2010 Nov;
164(2b):406-18.
PMID: 21091647
Background And Purpose: Systemic iron deficiency concomitant with macrophage iron retention is characteristic of iron-refractory anaemias associated with chronic disease. The systemic misdistribution of iron, which is further exacerbated by...
9.
Kakhlon O, Breuer W, Munnich A, Cabantchik Z
Can J Physiol Pharmacol
. 2010 Apr;
88(3):187-96.
PMID: 20393584
Defective iron utilization leading to either systemic or regional misdistribution of the metal has been identified as a critical feature of several different disorders. Iron concentrations can rise to toxic...
10.
Li H, Rybicki A, Suzuka S, von Bonsdorff L, Breuer W, Hall C, et al.
Nat Med
. 2010 Jan;
16(2):177-82.
PMID: 20098432
Individuals with beta-thalassemia develop progressive systemic iron overload, resulting in high morbidity and mortality. These complications are caused by labile plasma iron, which is taken up by parenchymal cells in...