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Wiktor Burdzinski

Explore the profile of Wiktor Burdzinski including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 25
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Recent Articles
1.
Szilagyi S, Burdzinski W, Jatzlau J, Ehrlich M, Knaus P, Henis Y
Cells . 2024 Feb; 13(3. PMID: 38334613
Mutations in activin-like kinase 2 (ALK2), e.g., ALK2-R206H, induce aberrant signaling to SMAD1/5/8, leading to Fibrodysplasia Ossificans Progressiva (FOP). In spite of extensive studies, the underlying mechanism is still unclear....
2.
Trumpp M, Tan W, Burdzinski W, Basler Y, Jatzlau J, Knaus P, et al.
PLoS One . 2023 Sep; 18(9):e0291379. PMID: 37708126
Activin and Bone Morphogenetic Protein (BMP) signaling plays crucial roles in vertebrate organ formation, including osteo- and angiogenesis, and tissue homeostasis, such as neuronal maintenance. Activin and BMP signaling needs...
3.
Jatzlau J, Burdzinski W, Trumpp M, Obendorf L, Rossmann K, Ravn K, et al.
Commun Biol . 2023 Jan; 6(1):34. PMID: 36635368
TGFβs, BMPs and Activins regulate numerous developmental and homeostatic processes and signal through hetero-tetrameric receptor complexes composed of two types of serine/threonine kinase receptors. Each of the 33 different ligands...
4.
Mendez P, Obendorf L, Jatzlau J, Burdzinski W, Reichenbach M, Nageswaran V, et al.
BMC Biol . 2022 Sep; 20(1):210. PMID: 36171573
Background: Fluid shear stress enhances endothelial SMAD1/5 signaling via the BMP9-bound ALK1 receptor complex supported by the co-receptor Endoglin. While moderate SMAD1/5 activation is required to maintain endothelial quiescence, excessive...
5.
Brunner P, Hastar N, Kaehler C, Burdzinski W, Jatzlau J, Knaus P
Mol Biol Cell . 2019 Dec; 31(2):118-130. PMID: 31800378
The large isoform of the transmembrane protein angiomotin (AMOT130) controls cell proliferation and migration of many cell types. AMOT130 associates to the actin cytoskeleton and regulates tight-junction maintenance and signaling...