Wiebke Arlt
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Explore the profile of Wiebke Arlt including associated specialties, affiliations and a list of published articles.
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297
Citations
10919
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Recent Articles
1.
Suntornlohanakul O, Mandal S, Saha P, Saygili E, Asia M, Arlt W, et al.
Eur J Endocrinol
. 2024 Oct;
191(5):481-490.
PMID: 39425921
Background: Adrenal masses are found in up to 5%-7% of adults. The 2016 European guidelines on the management of adrenal incidentalomas have standardised the workup of these patients, but evidence...
2.
Tomkins M, McDonnell T, Cussen L, Sagmeister M, Oestlund I, Shaheen F, et al.
J Clin Endocrinol Metab
. 2024 Oct;
PMID: 39382395
Context: 11-oxygenated androgens are a group of adrenal-derived steroids that require peripheral activation. In vitro data highlight a putative role for 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) in 11-oxygenated androgen biosynthesis,...
3.
Walchli-Popovic M, Monnerat S, Taylor A, Gilligan L, Schiffer L, Arlt W, et al.
Front Endocrinol (Lausanne)
. 2024 Sep;
15:1435698.
PMID: 39324125
Introduction: Chronic low-grade inflammation might contribute to hyperandrogenemia and metabolic complications in polycystic ovary syndrome (PCOS). The proinflammatory cytokine interleukin (IL)-1 stimulates androgen production from ovarian cells, whereas blockade of...
4.
Bizuneh A, Joham A, Teede H, Mousa A, Earnest A, Hawley J, et al.
Hum Reprod Update
. 2024 Sep;
31(1):48-63.
PMID: 39305127
Background: Biochemical hyperandrogenism is a hallmark and diagnostic feature of polycystic ovary syndrome (PCOS). However, the most accurate androgen measurement for assessing biochemical hyperandrogenism in PCOS diagnosis remains uncertain. Objective...
5.
Elhassan Y, Appenzeller S, Landwehr L, Lippert J, Popat D, Gilligan L, et al.
Eur J Endocrinol
. 2024 Aug;
191(3):334-344.
PMID: 39171930
Background: Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of Cushing's syndrome. Individuals with PBMAH and glucose-dependent insulinotropic polypeptide (GIP)-dependent Cushing's syndrome due to ectopic expression of the...
6.
7.
Rees D, Merke D, Arlt W, Brac de la Perriere A, Linden Hirschberg A, Juul A, et al.
Endocr Connect
. 2024 Jun;
13(8).
PMID: 38934378
Background: Prednisolone and prednisone are recommended treatment options for adults with congenital adrenal hyperplasia (CAH); however, there is no randomised comparison of prednis(ol)one with hydrocortisone. Design: Six-month open-label randomised phase...
8.
Timmerman S, Mullen N, Taylor A, Gilligan L, Pyle M, Shrestha T, et al.
bioRxiv
. 2024 May;
PMID: 38766205
Introduction: Aldosterone-producing adenoma (APA) is the most common cause of endocrine-related hypertension but surgery is not always feasible. Current medical interventions are associated with significant side effects and poor patient...
9.
Schiffer L, Arlt W, Storbeck K
J Steroid Biochem Mol Biol
. 2024 Apr;
241:106516.
PMID: 38582131
Epitestosterone is a stereoisomer of the active androgen testosterone and its circulating concentrations are similar to those of testosterone in women and children. However, its biological function and pathways of...
10.
Schiffer L, Oestlund I, Snoep J, Gilligan L, Taylor A, Sinclair A, et al.
FASEB J
. 2024 Mar;
38(7):e23574.
PMID: 38551804
Aldo-keto reductase 1C3 (AKR1C3) is a key enzyme in the activation of both classic and 11-oxygenated androgens. In adipose tissue, AKR1C3 is co-expressed with 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1), which...