Wibke Bayer
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Explore the profile of Wibke Bayer including associated specialties, affiliations and a list of published articles.
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44
Citations
398
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Recent Articles
1.
Wang X, Aurich K, Zhang W, Ehrhardt A, Greinacher A, Bayer W
Viruses
. 2024 Nov;
16(11).
PMID: 39599861
Adenoviruses are important human pathogens that are widespread and mainly associated with respiratory and gastrointestinal infections. In a previous study on human adenovirus (HAdV) seroprevalence, we observed reduced binding antibody...
2.
Wang X, Klann P, Wiedtke E, Sano Y, Fischer N, Schiller L, et al.
Front Immunol
. 2024 Oct;
15:1450858.
PMID: 39399494
High levels of pre-existing antibodies are a major challenge for the application of viral vectors since they can severely limit their efficacy. To identify promising candidates among adeno-associated virus (AAV)...
3.
Vieira Antao A, Oltmanns F, Schmidt A, Viherlehto V, Irrgang P, Rameix-Welti M, et al.
Front Immunol
. 2024 Jul;
15:1376395.
PMID: 38975350
Influenza A Virus (IAV) and Respiratory Syncytial Virus (RSV) are both responsible for millions of severe respiratory tract infections every year worldwide. Effective vaccines able to prevent transmission and severe...
4.
Erdemci-Evin S, Bosso M, Krchlikova V, Bayer W, Regensburger K, Mayer M, et al.
Viruses
. 2024 Apr;
16(4).
PMID: 38675836
PYHIN proteins are only found in mammals and play key roles in the defense against bacterial and viral pathogens. The corresponding gene locus shows variable deletion and expansion ranging from...
5.
Oltmanns F, Vieira Antao A, Irrgang P, Viherlehto V, Jorg L, Schmidt A, et al.
J Immunother Cancer
. 2024 Mar;
12(3).
PMID: 38458636
Background: Generally, early-stage breast cancer has a good prognosis. However, if it spreads systemically, especially with pulmonary involvement, prospects worsen dramatically. Importantly, tumor-infiltrating T cells contribute to tumor control, particularly...
6.
Wang X, Hetzel M, Zhang W, Ehrhardt A, Bayer W
Front Immunol
. 2023 Nov;
14:1286622.
PMID: 37915567
For the development of new adenovirus (AdV)-based vectors, it is important to understand differences in immunogenicity. In a side-by-side analysis, we evaluated the effect of 40 AdV types covering human...
7.
Malyshkina A, Bayer W, Podschwadt P, Otto L, Karakoese Z, Sutter K, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1011725.
PMID: 37883584
Antiretroviral therapy (ART) transformed HIV from a life-threatening disease to a chronic condition. However, eliminating the virus remains an elusive therapy goal. For several decades, Friend virus (FV) infection serves...
8.
Klann P, Wang X, Elfert A, Zhang W, Kohler C, Guttsches A, et al.
Viruses
. 2023 Jan;
15(1).
PMID: 36680119
High pre-existing antibodies against viral vectors reduce their functionality and may lead to adverse complications. To circumvent this problem in future gene therapy approaches, we tested the seroprevalence of a...
9.
Podschwadt P, Malyshkina A, Windmann S, Papadamakis A, Kerkmann L, Lapuente D, et al.
Front Immunol
. 2023 Jan;
13:934399.
PMID: 36605206
Retroviral envelope (Env) proteins have long been recognized to exhibit immunosuppressive properties, which affect the CD8 T-cell response to an infection but also to immunization. Interestingly, we previously showed in...
10.
Podschwadt P, Malyshkina A, Windmann S, Werner T, Hansen W, Bayer W
Retrovirology
. 2022 Dec;
19(1):29.
PMID: 36527061
Background: Friend virus (FV) is a complex of the Friend murine leukemia virus (F-MuLV) and the replication-defective, pathogenic spleen focus forming virus (SFFV). In the past, we used a fluorescently...