Whitney Rabacal
Overview
Explore the profile of Whitney Rabacal including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
219
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Recent Articles
1.
Rayens E, Rabacal W, Willems H, Kirton G, Barber J, Mousa J, et al.
PNAS Nexus
. 2023 Jan;
1(5):pgac248.
PMID: 36712332
Invasive fungal infections cause over 1.5 million deaths worldwide. Despite increases in fungal infections as well as the numbers of individuals at risk, there are no clinically approved fungal vaccines....
2.
Rabacal W, Schweitzer F, Kling H, Buzzelli L, Rayens E, Norris K
Front Immunol
. 2022 Dec;
13:1036658.
PMID: 36561749
Introduction: is a ubiquitous fungal pathogen that causes pneumonia (PCP) and pulmonary sequelae in HIV-infected individuals and other immunocompromised populations. With the success of anti-retroviral therapy for HIV-infected individuals the...
3.
Rayens E, Rabacal W, Kang S, Celia B, Momany M, Norris K
Front Immunol
. 2021 Jun;
12:670578.
PMID: 34084170
Life-threatening, invasive fungal infections (IFIs) cause over 1.5 million deaths worldwide and are a major public health concern with high mortality rates even with medical treatment. Infections with the opportunistic...
4.
Rabacal W, Schweitzer F, Rayens E, Tarantelli R, Whang P, Cobos Jimenez V, et al.
Sci Rep
. 2019 Dec;
9(1):19832.
PMID: 31882598
Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by pulmonary vascular remodeling, elevated pulmonary arterial pressure, and right heart failure. Human immunodeficiency virus (HIV)-infected individuals have a higher incidence...
5.
Cobos Jimenez V, Rabacal W, Rayens E, Norris K
Hum Vaccin Immunother
. 2019 Jul;
15(9):2075-2080.
PMID: 31348719
Infection with the opportunistic fungal pathogen, causes life-threatening pneumonia in immunocompromised individuals. In addition to HIV-1 infected patients, individuals at risk of infection include those receiving immunosuppressive therapies due to...
6.
Guo Y, Luan L, Patil N, Wang J, Bohannon J, Rabacal W, et al.
J Immunol
. 2016 Dec;
198(3):1320-1333.
PMID: 28031340
Interleukin 15 is essential for the development and differentiation of NK and memory CD8 (mCD8) T cells. Our laboratory previously showed that NK and CD8 T lymphocytes facilitate the pathobiology...
7.
Pabbisetty S, Rabacal W, Volanakis E, Parekh V, Olivares-Villagomez D, Cendron D, et al.
Proc Natl Acad Sci U S A
. 2016 Jul;
113(32):E4662-70.
PMID: 27462110
Tregs are essential for maintaining peripheral tolerance, and thus targeting these cells may aid in the treatment of autoimmunity and cancer by enhancing or reducing suppressive functions, respectively. Before these...
8.
Rabacal W, Pabbisetty S, Hoek K, Cendron D, Guo Y, Maseda D, et al.
Proc Natl Acad Sci U S A
. 2016 Apr;
113(19):5370-5.
PMID: 27114551
Natural killer (NK) cells are innate lymphocytes that recognize and lyse virally infected or transformed cells. This latter property is being pursued in clinics to treat leukemia with the hope...
9.
Guo Y, Luan L, Rabacal W, Bohannon J, Fensterheim B, Hernandez A, et al.
J Immunol
. 2015 Jul;
195(5):2353-64.
PMID: 26216888
IL-15 is currently undergoing clinical trials to assess its efficacy for treatment of advanced cancers. The combination of IL-15 with soluble IL-15Rα generates a complex termed IL-15 superagonist (IL-15 SA)...
10.
Pabbisetty S, Rabacal W, Maseda D, Cendron D, Collins P, Hoek K, et al.
Proc Natl Acad Sci U S A
. 2014 Jul;
111(26):9579-84.
PMID: 24979767
Regulatory T cells (Tregs) are a specialized subset of CD4(+) T cells that maintain self-tolerance by functionally suppressing autoreactive lymphocytes. The Treg compartment is composed of thymus-derived Tregs (tTregs) and...