Wesam S Qayed
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Explore the profile of Wesam S Qayed including associated specialties, affiliations and a list of published articles.
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12
Citations
26
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Recent Articles
1.
Abdu-Allah H, El-Nagar M, Qayed W, Salem O, Kafafy A, El-Awady R, et al.
Chem Biol Drug Des
. 2025 Jan;
105(1):e70052.
PMID: 39865457
Target cyclooxygenase 2 (COX-2) and 5-lipoxygenase (5-LOX) inhibitors; 5-([2,5-Dihydroxybenzyl]amino)salicylamides (Compounds 1-11) were examined for potential anticancer activity, with a trial to assess the underlying possible mechanisms. Compounds were assessed at...
2.
Shin S, Ye M, Chae M, Geum S, Aboraia A, Abdel-Aal A, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335479
Allergic rhinitis (AR) is a common chronic disease that significantly impacts the quality of life. Lidocaine is known to have anti-inflammatory and immunomodulatory effects. This study evaluated the effect of...
3.
Shin S, Ye M, Chae M, Geum S, Aboraia A, Abdel-Aal A, et al.
Molecules
. 2023 Aug;
28(15).
PMID: 37570665
Lidocaine, a local anesthetic, is known to possess anti-inflammatory properties. However, its clinical use is limited by inconveniences, such as its local synesthetic effects. This study evaluated lidocaine analogs designed...
4.
Hosny N, Gadallah M, Qayed W
Luminescence
. 2023 May;
38(8):1449-1457.
PMID: 37222106
Empagliflozin (EMP) is an oral antihyperglycemic agent for type 2 diabetic patients. The molecular binding of EMP to bovine serum albumin (BSA) was elucidated by a combined experimental/computational approach to...
5.
Balieiro A, Anunciacao E, Costa C, Qayed W, Silva J
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430451
Methyltransferases (MTases) enzymes, responsible for RNA capping into severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are emerging important targets for the design of new anti-SARS-CoV-2 agents. Here, analogs of S-adenosylmethionine...
6.
Sayed H, Ahmed A, Khallaf I, Qayed W, Mohammed A, Farghaly H, et al.
J Ethnopharmacol
. 2022 Nov;
303:115938.
PMID: 36410572
Ethnopharmacological Relevance: Gmelina philippensis CHAM is an ornamental plant that is distributed in South Asia and warm regions of the Mediterranean area. The plant is traditionally applied in folk medicine...
7.
Qayed W, Ferreira R, Silva J
Molecules
. 2022 Sep;
27(18).
PMID: 36144718
The SARS-CoV-2 targets were evaluated for a set of FDA-approved drugs using a combination of drug repositioning and rigorous computational modeling methodologies such as molecular docking and molecular dynamics (MD)...
8.
Qayed W, Hassan M, El-Sayed W, Silva J, Aboul-Fadl T
Bioorg Chem
. 2022 May;
126:105884.
PMID: 35623140
Molecular hybrid of 2-indolinone-thiazolidinone is a well known scaffold for variable biological activities including anticancer activity. Accordingly, in the current work aided with structure-based molecular modeling studies, a library of...
9.
Hassan S, Gad S, Abdu-Allah H, Qayed W, Abouelmagd S, Ibrahim E
Int J Pharm
. 2022 Apr;
620:121724.
PMID: 35405279
Efficiency of drug delivery is product of drug properties and formulation design. Modulating drug's unfavorable properties such as poor solubility or permeation is the first step towards optimum delivery. By...
10.
Yousef M, Ali A, El-Sayed W, Qayed W, Farag H, Aboul-Fadl T
Bioorg Chem
. 2022 Jan;
120:105598.
PMID: 35032748
No abstract available.