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Werner Kilb

Explore the profile of Werner Kilb including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 1964
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Recent Articles
1.
Abusaada A, De Rosa F, Luhmann H, Kilb W, Sinning A
Front Cell Neurosci . 2025 Mar; 19:1556174. PMID: 40078325
GABA is an essential element in the function of neocortical circuits. The origin, migration and mechanisms of synaptogenesis of GABAergic neurons have been intensively studied. However, little information is available...
2.
Lombardi A, Wang Q, Stuttgen M, Mittmann T, Luhmann H, Kilb W
Front Cell Neurosci . 2023 Oct; 17:1254776. PMID: 37817883
Introduction: Short-term synaptic plasticity (STP) is a widespread mechanism underlying activity-dependent modifications of cortical networks. Methods: To investigate how STP influences excitatory and inhibitory synapses in layer 2/3 of mouse...
3.
Neuwirth L, El Idrissi A, Fukuda A, Kilb W
Front Mol Neurosci . 2023 Mar; 16:1162689. PMID: 36926282
No abstract available.
4.
Gellert L, Luhmann H, Kilb W
Front Neuroanat . 2023 Feb; 17:1105998. PMID: 36760662
The development of functionally interconnected networks between primary (S1), secondary somatosensory (S2), and motor (M1) cortical areas requires coherent neuronal activity corticocortical projections. However, the anatomical substrate of functional connections...
5.
Kilb W, Kirischuk S
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555501
Astrocytes are the most abundant glial cells in the central nervous system (CNS) mediating a variety of homeostatic functions, such as spatial K buffering or neurotransmitter reuptake. In addition, astrocytes...
6.
Kilb W
Front Mol Neurosci . 2021 Dec; 14:747835. PMID: 34899178
The membrane responses upon activation of GABA(A) receptors critically depend on the intracellular Cl concentration ([Cl]), which is maintained by a set of transmembrane transporters for Cl. During neuronal development,...
7.
Lombardi A, Luhmann H, Kilb W
PLoS Comput Biol . 2021 Nov; 17(11):e1009199. PMID: 34767548
GABA (γ-amino butyric acid) is an inhibitory neurotransmitter in the adult brain that can mediate depolarizing responses during development or after neuropathological insults. Under which conditions GABAergic membrane depolarizations are...
8.
Huang W, Ke Y, Zhu J, Liu S, Cong J, Ye H, et al.
Cell Rep . 2021 Jul; 36(3):109404. PMID: 34289346
Glutamatergic and GABAergic synaptic transmission controls excitation and inhibition of postsynaptic neurons, whereas activity of ion channels modulates neuronal intrinsic excitability. However, it is unclear how excessive neuronal excitation affects...
9.
Wong Fong Sang I, Schroer J, Halbhuber L, Warm D, Yang J, Luhmann H, et al.
Int J Mol Sci . 2021 Jul; 22(12). PMID: 34205237
A substantial proportion of neurons undergoes programmed cell death (apoptosis) during early development. This process is attenuated by increased levels of neuronal activity and enhanced by suppression of activity. To...
10.
Lombardi A, Jedlicka P, Luhmann H, Kilb W
PLoS Comput Biol . 2021 Jan; 17(1):e1008573. PMID: 33465082
The impact of GABAergic transmission on neuronal excitability depends on the Cl--gradient across membranes. However, the Cl--fluxes through GABAA receptors alter the intracellular Cl- concentration ([Cl-]i) and in turn attenuate...