Wenxuan Hong
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Explore the profile of Wenxuan Hong including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
218
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Recent Articles
1.
Bao Q, Wang A, Hong W, Wang Y, Li B, He L, et al.
Cell Commun Signal
. 2024 Apr;
22(1):247.
PMID: 38689280
Background: Renal fibrosis is a prevalent manifestation of chronic kidney disease (CKD), and effective treatments for this disease are currently lacking. Myofibroblasts, which originate from interstitial fibroblasts, aggregate in the...
2.
Liu H, Yue L, Hong W, Zhou J
Life Sci
. 2024 Apr;
347:122605.
PMID: 38642845
Aims: Hepatocellular carcinoma (HCC) is a lead cause of cancer-related deaths. In the present study we investigated the role of Brahma-related gene 1 (BRG1), a chromatin remodeling protein, in HCC...
3.
Zhao Q, Shao T, Huang S, Zhang J, Zong G, Zhuo L, et al.
Br J Pharmacol
. 2024 Apr;
181(15):2492-2508.
PMID: 38586912
Background And Purpose: Excessive fibrogenesis is associated with adverse cardiac remodelling and heart failure. The myofibroblast, primarily derived from resident fibroblast, is the effector cell type in cardiac fibrosis. Megakaryocytic...
4.
Hong W, Zhu Y, Lin Y, Tang S, Chen J, Xu L, et al.
Life Sci
. 2024 Jan;
340:122320.
PMID: 38272440
Aims: Renal fibrosis is an important pathophysiological process commonly observed in patients chronic kidney disease (CKD). Angiotensin II (Ang II) is a major risk factor for CKD in part by...
5.
Zhang J, Liu L, Dong Z, Lu X, Hong W, Liu J, et al.
Bioact Mater
. 2023 Jul;
28:480-494.
PMID: 37408796
Myocardial ischemia-reperfusion (MI/R) injury is common in patients who undergo revascularization therapy for myocardial infarction, often leading to cardiac dysfunction. Carbon monoxide (CO) has emerged as a therapeutic molecule due...
6.
Liu J, Pan L, Hong W, Chen S, Bai P, Luo W, et al.
Nat Commun
. 2022 Dec;
13(1):7519.
PMID: 36473866
Regulatory T cells (Tregs) are critically involved in neovascularization, an important compensatory mechanism in peripheral artery disease. The contribution of G protein coupled receptor 174 (GPR174), which is a regulator...
7.
Liu C, Tang J, Luo W, Liu S, Sun X, Hong W, et al.
Rheumatology (Oxford)
. 2022 Jun;
62(2):934-945.
PMID: 35686918
Objective: To clarify the role of RNA polymerase III A (POLR3A)/type I IFN in the pathogenesis of SSc. Methods: Cytosolic DNA and stimulator of IFN genes (STING) pathway in skin...
8.
Miao X, Guo Y, Zeng S, Liu X, Teng X, Li L, et al.
Cell Death Discov
. 2021 Oct;
7(1):308.
PMID: 34689159
Non-alcoholic fatty liver disease (NAFLD) is prototypical form of metabolic syndrome and has become a global pandemic. Hepatocytes undergo apoptosis in the pathogenesis of NAFLD. We report that the lymphokine...
9.
Hong W, Kong M, Qi M, Bai H, Fan Z, Zhang Z, et al.
Front Cell Dev Biol
. 2021 Feb;
8:587502.
PMID: 33553140
Fulminant hepatitis (FH) is a major cause of acute liver failure. Concanavalin A (ConA) belongs to the lectin family and is frequently used as an inducer of FH in animal...
10.
Fan Z, Kong M, Li M, Hong W, Fan X, Xu Y
Front Cell Dev Biol
. 2020 Jun;
8:259.
PMID: 32500071
Hepatocyte is a hub for cholesterol metabolism. Augmented synthesis of cholesterol in the liver is associated with hypercholesterolemia and contributes to the pathogenesis of a host of cardiovascular and metabolic...