Wenwu Cui
Overview
Explore the profile of Wenwu Cui including associated specialties, affiliations and a list of published articles.
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12
Citations
1501
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Recent Articles
1.
Stanley J, Lohith A, Debiaso L, Wang K, Ton M, Cui W, et al.
PLoS One
. 2023 Aug;
18(8):e0289279.
PMID: 37527243
Single-cell transcriptomics is essential for understanding biological variability among cells in a heterogenous population. Acquiring high-quality single-cell sequencing data from a tissue sample has multiple challenges including isolation of individual...
2.
Jaganathan K, Kyriazopoulou Panagiotopoulou S, McRae J, Fazel Darbandi S, Knowles D, Li Y, et al.
Cell
. 2019 Jan;
176(3):535-548.e24.
PMID: 30661751
The splicing of pre-mRNAs into mature transcripts is remarkable for its precision, but the mechanisms by which the cellular machinery achieves such specificity are incompletely understood. Here, we describe a...
3.
Kupershmidt I, Su Q, Grewal A, Sundaresh S, Halperin I, Flynn J, et al.
PLoS One
. 2010 Oct;
5(9).
PMID: 20927376
Background: The investigation of the interconnections between the molecular and genetic events that govern biological systems is essential if we are to understand the development of disease and design effective...
4.
Byun J, Wong M, Cui W, Idelman G, Li Q, De Siervi A, et al.
Proc Natl Acad Sci U S A
. 2009 Nov;
106(46):19286-91.
PMID: 19880750
Profiling the dynamic interaction of p300 with proximal promoters of human T cells identified a class of genes that rapidly coassemble p300 and RNA polymerase II (pol II) following mitogen...
5.
Tongbai R, Idelman G, Nordgard S, Cui W, Jacobs J, Haggerty C, et al.
Am J Pathol
. 2008 Jan;
172(2):495-509.
PMID: 18187569
Global genomic approaches in cancer research have provided new and innovative strategies for the identification of signatures that differentiate various types of human cancers. Computational analysis of the promoter composition...
6.
Cui W, Taub D, Gardner K
Nucleic Acids Res
. 2006 Oct;
35(Database issue):D805-9.
PMID: 17068075
Gene expression studies employing high throughput real time PCR methods require finding uniform conditions for optimal amplification of multiple targets, often a daunting task. We developed a primer database, qPrimerDepot,...
7.
Ge Y, Montano I, Rustici G, Freebern W, Haggerty C, Cui W, et al.
Blood
. 2006 Aug;
108(13):4126-35.
PMID: 16940421
Using a novel cell-based assay to profile transcriptional pathway targeting, we have identified a new functional class of thalidomide analogs with distinct and selective antileukemic activity. These agents activate nuclear...
8.
McNutt M, Tongbai R, Cui W, Collins I, Freebern W, Montano I, et al.
BMC Bioinformatics
. 2005 Oct;
6:259.
PMID: 16232321
Background: The purpose of this study is to determine whether or not there exists nonrandom grouping of cis-regulatory elements within gene promoters that can be perceived independent of gene expression...
9.
Duncan M, Xie L, David L, Robinson M, Taube J, Cui W, et al.
Invest Ophthalmol Vis Sci
. 2004 Sep;
45(10):3589-98.
PMID: 15452066
Purpose: Pax6 is a transcription factor necessary for the specification and subsequent formation of the ocular lens. It is expressed in all lens cells at early stages of development. After...
10.
Cui W, Ning J, Naik U, Duncan M
Comput Methods Programs Biomed
. 2004 May;
75(1):67-73.
PMID: 15158049
RNA interference (RNAi), a recently developed reverse genetics tool, has many advantages compared to traditional gene knockout methods. Appropriate selection of double stranded RNAs identical to a specific region(s) of...