Wenjian Bi
Overview
Explore the profile of Wenjian Bi including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
758
Followers
0
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Recent Articles
1.
Sun Y, Liao Y, Zhang Y, Lu Z, Ma Y, Kang Z, et al.
Nat Commun
. 2025 Feb;
16(1):1748.
PMID: 39966400
Childhood maltreatment stands out as a pivotal risk factor for depression, with gene-by-environment interaction serving as a crucial mechanism. Here we perform genome-wide interaction analyzes of childhood maltreatment in the...
2.
Xu H, Ma Y, Xu L, Li Y, Liu Y, Li Y, et al.
Nat Commun
. 2025 Feb;
16(1):1413.
PMID: 39915470
Sample relatedness is a major confounder in genome-wide association studies (GWAS), potentially leading to inflated type I error rates if not appropriately controlled. A common strategy is to incorporate a...
3.
Sun Y, Zhang Y, Lu Z, Liao Y, Feng Q, Yu M, et al.
EBioMedicine
. 2024 Jun;
105:105195.
PMID: 38870545
Background: Response to antipsychotic drugs (APD) varies greatly among individuals and is affected by genetic factors. This study aims to demonstrate genome-wide associations between copy number variants (CNVs) and response...
4.
Bi W, Xu Z, Liu F, Xie Z, Liu H, Zhu X, et al.
PLoS Genet
. 2024 Jan;
20(1):e1011134.
PMID: 38241355
It has been well established that cancer cells can evade immune surveillance by mutating themselves. Understanding genetic alterations in cancer cells that contribute to immune regulation could lead to better...
5.
Bi W, Zhou W, Zhang P, Sun Y, Yue W, Lee S
Am J Hum Genet
. 2023 Apr;
110(5):762-773.
PMID: 37019109
The ongoing release of large-scale sequencing data in the UK Biobank allows for the identification of associations between rare variants and complex traits. SAIGE-GENE+ is a valid approach to conducting...
6.
Zhou W, Bi W, Zhao Z, Dey K, Jagadeesh K, Karczewski K, et al.
Nat Genet
. 2022 Oct;
54(11):1755.
PMID: 36257984
No abstract available.
7.
Sun Y, Zhang Y, Lu Z, Yan H, Guo L, Liao Y, et al.
Schizophr Bull
. 2022 Sep;
49(1):208-217.
PMID: 36179110
Background And Hypothesis: Complex schizophrenia symptoms were recently conceptualized as interactive symptoms within a network system. However, it remains unknown how a schizophrenia network changed during acute antipsychotic treatment. The...
8.
Zhou W, Bi W, Zhao Z, Dey K, Jagadeesh K, Karczewski K, et al.
Nat Genet
. 2022 Sep;
54(10):1466-1469.
PMID: 36138231
Several biobanks, including UK Biobank (UKBB), are generating large-scale sequencing data. An existing method, SAIGE-GENE, performs well when testing variants with minor allele frequency (MAF) ≤ 1%, but inflation is...
9.
Zhuang Y, Wolford B, Nam K, Bi W, Zhou W, Willer C, et al.
Bioinformatics
. 2022 Jul;
38(18):4337-4343.
PMID: 35876838
Motivation: In the genome-wide association analysis of population-based biobanks, most diseases have low prevalence, which results in low detection power. One approach to tackle the problem is using family disease...
10.
Shi X, Teng H, Shi L, Bi W, Wei W, Mao F, et al.
Brief Bioinform
. 2022 Jan;
23(2).
PMID: 35037014
Optimal methods could effectively improve the accuracy of predicting and identifying candidate driver genes. Various computational methods based on mutational frequency, network and function approaches have been developed to identify...