Wenchun Chen
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Explore the profile of Wenchun Chen including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
384
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Recent Articles
1.
Chen W, Peng K, Huang M, Zhao J, Zhang Z, Guo H, et al.
Sheng Wu Gong Cheng Xue Bao
. 2024 Dec;
40(12):4628-4644.
PMID: 39722522
To clarify the genetic diversity and structure of the nucleus population of F1-generation , this study utilized 15 pairs of highly polymorphic microsatellite primers to analyze the simple sequence repeat...
2.
Duan Y, Szlam F, Hu Y, Chen W, Li R, Ke Y, et al.
Nat Biomed Eng
. 2023 Nov;
7(11):1404-1418.
PMID: 37957275
Molecular forces generated by cell receptors are infrequent and transient, and hence difficult to detect. Here we report an assay that leverages the CRISPR-associated protein 12a (Cas12a) to amplify the...
3.
Lu H, Chen W, Peng K, Huang M, Zhao J, Chen X, et al.
Comp Biochem Physiol Part D Genomics Proteomics
. 2023 Oct;
48:101149.
PMID: 37883838
The Pacific white shrimp (Litopenaeus vannamei) is a euryhaline crustacean capable of tolerating a wide range of ambient salinity, but the strategies of hepatopancreas to rapid adaptive or acute stimulatory...
4.
Ma R, Rashid S, Velusamy A, Deal B, Chen W, Petrich B, et al.
Nat Methods
. 2023 Oct;
20(11):1666-1671.
PMID: 37798479
Flow cytometry is used routinely to measure single-cell gene expression by staining cells with fluorescent antibodies and nucleic acids. Here, we present tension-activated cell tagging (TaCT) to label cells fluorescently...
5.
Arce N, Liu Y, Chen W, Zhang X, Li R
J Thromb Haemost
. 2022 Aug;
20(11):2686-2696.
PMID: 36031939
Background: Von Willebrand factor (VWF) is a multimeric plasma protein that bridges the gap between vessel injury and platelet capture at high shear rates. Under high shear or tension, VWF...
6.
Chen W, Wilson M, Wang Y, Bergmeier W, Lanza F, Li R
J Thromb Haemost
. 2022 Mar;
20(6):1451-1463.
PMID: 35305057
Background: Glycoprotein (GP)Ibα plays a critical role in regulating platelet clearance. Recently, we identified the mechanosensory domain (MSD) in GPIbα and reported evidence to suggest that unfolding of the GPIbα...
7.
Blanchard A, Combs J, Brockman J, Kellner A, Glazier R, Su H, et al.
Nat Commun
. 2021 Sep;
12(1):5600.
PMID: 34531385
No abstract available.
8.
Blanchard A, Combs J, Brockman J, Kellner A, Glazier R, Su H, et al.
Nat Commun
. 2021 Aug;
12(1):4693.
PMID: 34344862
Many cellular processes, including cell division, development, and cell migration require spatially and temporally coordinated forces transduced by cell-surface receptors. Nucleic acid-based molecular tension probes allow one to visualize the...
9.
Hu Y, Ma V, Ma R, Chen W, Duan Y, Glazier R, et al.
Angew Chem Int Ed Engl
. 2021 May;
60(33):18044-18050.
PMID: 33979471
Mechanotransduction, the interplay between physical and chemical signaling, plays vital roles in many biological processes. The state-of-the-art techniques to quantify cell forces employ deformable polymer films or molecular probes tethered...
10.
Quach M, Chen W, Wang Y, Deckmyn H, Lanza F, Nieswandt B, et al.
J Thromb Haemost
. 2021 Apr;
19(8):2044-2055.
PMID: 33915031
Background: Platelets' initial recognition of endothelial damage proceeds through the interaction between collagen, plasma von Willebrand factor (VWF), and the platelet glycoprotein (GP)Ib-IX complex (CD42). The GPIb-IX complex consists of...