Anum K Syed
Overview
Explore the profile of Anum K Syed including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
214
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0
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Recent Articles
1.
Syed A, Whisenant J, Barnes S, Sorace A, Yankeelov T
Cancers (Basel)
. 2020 Jul;
12(6).
PMID: 32599906
This study identifies physiological tumor habitats from quantitative magnetic resonance imaging (MRI) data and evaluates their alterations in response to therapy. Two models of breast cancer (BT-474 and MDA-MB-231) were...
2.
Bloom M, Jarrett A, Triplett T, Syed A, Davis T, Yankeelov T, et al.
BMC Cancer
. 2020 Apr;
20(1):359.
PMID: 32345237
Background: Therapy targeted to the human epidermal growth factor receptor type 2 (HER2) is used in combination with cytotoxic therapy in treatment of HER2+ breast cancer. Trastuzumab, a monoclonal antibody...
3.
Quach M, Syed A, Li R
J Vis Exp
. 2019 Jun;
(148).
PMID: 31233025
Many biological cells/tissues sense the mechanical properties of their local environments via mechanoreceptors, proteins that can respond to forces like pressure or mechanical perturbations. Mechanoreceptors detect their stimuli and transmit...
4.
Syed A, Woodall R, Whisenant J, Yankeelov T, Sorace A
Neoplasia
. 2018 Nov;
21(1):17-29.
PMID: 30472501
The purpose of this study is to investigate imaging and histology-based measurements of intratumoral heterogeneity to evaluate early treatment response to targeted therapy in a murine model of HER2+ breast...
5.
Jarrett A, Bloom M, Godfrey W, Syed A, Ekrut D, Ehrlich L, et al.
Math Med Biol
. 2018 Sep;
36(3):381-410.
PMID: 30239754
The goal of this study is to develop an integrated, mathematical-experimental approach for understanding the interactions between the immune system and the effects of trastuzumab on breast cancer that overexpresses...
6.
Quach M, Dragovich M, Chen W, Syed A, Cao W, Liang X, et al.
Blood
. 2017 Dec;
131(7):787-796.
PMID: 29203584
Immune thrombocytopenia (ITP) is a prevalent autoimmune disease characterized by autoantibody-induced platelet clearance. Some ITP patients are refractory to standard immunosuppressive treatments such as intravenous immunoglobulin (IVIg). These patients often...
7.
Deng W, Xu Y, Chen W, Paul D, Syed A, Dragovich M, et al.
Nat Commun
. 2016 Sep;
7:12863.
PMID: 27670775
Mechanisms by which blood cells sense shear stress are poorly characterized. In platelets, glycoprotein (GP)Ib-IX receptor complex has been long suggested to be a shear sensor and receptor. Recently, a...
8.
Sorace A, Syed A, Barnes S, Quarles C, Sanchez V, Kang H, et al.
Mol Imaging Biol
. 2016 Aug;
19(1):130-137.
PMID: 27506906
Purpose: Evaluation of [F]fluoromisonidazole ([F]FMISO)-positron emission tomography (PET) imaging as a metric for evaluating early response to trastuzumab therapy with histological validation in a murine model of HER2+ breast cancer....
9.
Chen W, Liang X, Syed A, Jessup P, Church W, Ware J, et al.
Arterioscler Thromb Vasc Biol
. 2016 Jul;
36(9):1821-8.
PMID: 27417583
Objective: The platelet storage lesion accelerates platelet clearance after transfusion, but the underlying molecular mechanism remains elusive. Although inhibiting sheddase activity hampers clearance of platelets with storage lesion, the target...