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Wenbiao Wang

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Articles 55
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Recent Articles
31.
Wang W, Hu D, Feng Y, Wu C, Song Y, Liu W, et al.
BMC Biol . 2020 Nov; 18(1):182. PMID: 33243234
Background: Extracellular adenosine triphosphate (ATP), a key danger-associated molecular pattern (DAMP) molecule, is released to the extracellular medium during inflammation by injured parenchymal cells, dying leukocytes, and activated platelets. ATP...
32.
Tian M, Liu W, Zhang Q, Huang Y, Li W, Wang W, et al.
Cell Rep . 2020 Oct; 33(3):108297. PMID: 33086059
The immune system is not only required for preventing threats exerted by pathogens but also essential for developing immune tolerance to avoid tissue damage. This study identifies a distinct mechanism...
33.
Wang W, Zhou Z, Zhou X, Chen L, Bie S, Jing Z
AMB Express . 2020 Aug; 10(1):148. PMID: 32809085
Mukonal is an active member of carbazole alkaloids isolated from Murraya koenigii. It has been shown to possess remarkable biological and pharmacological activities including anticancer activity. Therefore, the aim of...
34.
Jin J, Wang W, Li A, Wu J
Biochem Biophys Res Commun . 2020 Aug; 531(2):152-159. PMID: 32782149
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) by coding pattern recognition receptors (PRRs). As a well-known inflammasome, NLRP3 plays an essential role in...
35.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, et al.
Virulence . 2020 May; 11(1):537-553. PMID: 32434419
Enterovirus 71 (EV71) infection causes hand, foot, and mouth disease (HFMD), and even fatal neurological complications. However, the mechanisms underlying EV71 neurological pathogeneses are largely unknown. This study reveals a...
36.
Wang W, Hu D, Wu C, Feng Y, Li A, Liu W, et al.
PLoS Pathog . 2020 Mar; 16(3):e1008335. PMID: 32187211
One of the fundamental reactions of the innate immune responses to pathogen infection is the release of pro-inflammatory cytokines, including IL-1β, processed by the NLRP3 inflammasome. The stimulator of interferon...
37.
Li A, Wang W, Wang Y, Chen K, Xiao F, Hu D, et al.
Front Immunol . 2020 Mar; 11:51. PMID: 32117232
During host-virus co-evolution, cells develop innate immune systems to inhibit virus invasion, while viruses employ strategies to suppress immune responses and maintain infection. Here, we reveal that Zika virus (ZIKV),...
38.
Li G, Fan Y, Lai Y, Han T, Li Z, Zhou P, et al.
J Med Virol . 2020 Jan; 92(4):424-432. PMID: 31981224
Coronaviruses (CoVs) are by far the largest group of known positive-sense RNA viruses having an extensive range of natural hosts. In the past few decades, newly evolved Coronaviruses have posed...
39.
Shao L, Liu Y, Wang W, Li A, Wan P, Liu W, et al.
FASEB J . 2020 Jan; 34(1):1497-1515. PMID: 31914638
The NLRP3 inflammasome regulates innate immune and inflammatory responses by promoting caspase1-dependent induction of pro-inflammatory cytokines. However, aberrant inflammasome activation causes diverse diseases, and thus inflammasome activity must be tightly...
40.
Jin J, Wang W, Ai S, Liu W, Song Y, Luo Z, et al.
Viruses . 2019 Dec; 12(1). PMID: 31878072
Enterovirus 71 (EV71) infection causes hand-foot-mouth disease (HFMD), meningoencephalitis, neonatal sepsis, and even fatal encephalitis in children, thereby presenting a serious risk to public health. It is important to determine...