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Wen-Yang Hu

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Recent Articles
1.
Pedersen C, Chen V, Herbst P, Zhang R, Elfert A, Krishan A, et al.
Ocul Surf . 2024 Oct; 34:459-476. PMID: 39426677
Extracellular vesicles, including exosomes, are small extracellular vesicles that range in size from 30 nm to 10 μm in diameter and have specific membrane markers. They are naturally secreted and...
2.
Lu S, Ma M, Yan X, Zhao F, Hu W, Ding Q, et al.
Vet Med (Praha) . 2023 Nov; 68(3):106-115. PMID: 37981902
Porcine deltacoronavirus (PDCoV) and porcine sapelovirus (PSV) are two viruses that can cause diarrhoea in pigs and bring great economic loss to the pig industry. In this research, a duplex...
3.
Patnam M, Dommaraju S, Masood F, Herbst P, Chang J, Hu W, et al.
Cells . 2023 Jan; 12(2). PMID: 36672254
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection. Following injury, corneal (lymph)angiogenic privilege is...
4.
Hu W, Liu L, Afradiasbagharani P, Lu R, Chen Z, Hu D, et al.
Am J Clin Exp Urol . 2023 Jan; 10(6):377-389. PMID: 36636689
Cancer stem cells (CSCs) are resistant to conventional cancer therapies, permitting the repopulation of new tumor growth and driving disease progression. Models for testing prostate CSC-propagated tumor growth are presently...
5.
Masood F, Chang J, Akbar A, Song A, Hu W, Azar D, et al.
Cells . 2022 Oct; 11(20). PMID: 36291115
Limbal stem cells constitute an important cell population required for regeneration of the corneal epithelium. If insults to limbal stem cells or their niche are sufficiently severe, a disease known...
6.
Hu W, Lu R, Hu D, Imir O, Zuo Q, Moline D, et al.
Biochem Pharmacol . 2021 Dec; 197:114902. PMID: 34968493
Per- and polyfluorinated alkyl substances (PFAS) are a large family of widely used synthetic chemicals that are environmentally and biologically persistent and present in most individuals. Chronic PFAS exposure have...
7.
Hu W, Afradiasbagharani P, Lu R, Liu L, Birch L, Prins G
Biomolecules . 2021 Dec; 11(12). PMID: 34944473
The molecular mechanisms underlying prostate development can provide clues for prostate cancer research. It has been demonstrated that MEK/ERK signaling downstream of androgen-targeted FGF10 signaling directly induces prostatic branching during...
8.
Imir O, Kaminsky A, Zuo Q, Liu Y, Singh R, Spinella M, et al.
Nutrients . 2021 Nov; 13(11). PMID: 34836157
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals utilized in various industrial settings and include products such as flame retardants, artificial film-forming foams, cosmetics, and non-stick cookware, among others. Epidemiological...
9.
Hu W, Hu D, Xie L, Nonn L, Lu R, Abern M, et al.
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360875
Single prostate stem cells can generate stem and progenitor cells to form prostaspheres in 3D culture. Using a prostasphere-based label retention assay, we recently identified keratin 13 ()-enriched prostate stem...
10.
Qin Z, Ou S, Xu L, Sorensen K, Zhang Y, Hu D, et al.
Chem Biol Drug Des . 2021 Jan; 97(5):1059-1078. PMID: 33470049
Sustained androgen receptor (AR) signaling and apoptosis evasion are among the main hurdles of castration-resistant prostate cancer (CRPC) treatment. We designed and synthesized isothiocyanate (ITC)-containing hybrid AR antagonist (ITC-ARi) and...