Wen-Wen Shen
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Explore the profile of Wen-Wen Shen including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
179
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Recent Articles
1.
Ou Z, Wang K, Shen W, Deng G, Xu Y, Wang L, et al.
Biochem Pharmacol
. 2023 Feb;
210:115458.
PMID: 36803956
Oncogene FLT3 internal tandem duplication (FLT3-ITD) mutation accounts for 30 % of acute myeloid leukaemia (AML) cases and induces transformation. Previously, we found that E2F transcription factor 1 (E2F1) was...
2.
Yang L, Shen W, Shao W, Zhao Q, Pang G, Yang Y, et al.
Acta Pharmacol Sin
. 2023 Jan;
44(6):1175-1190.
PMID: 36635421
Mesencephalic astrocyte-derived neurotrophic factor (MANF), an endoplasmic reticulum stress-inducible secreting protein, has evolutionarily conserved immune-regulatory function that contributes to the negative regulation of inflammation in macrophages. In this study, we...
3.
Liu Z, Tian L, Sun X, Liu Z, Hao L, Shen W, et al.
World J Gastroenterol
. 2022 Sep;
28(33):4846-4860.
PMID: 36156930
Background: The frequency of acute hypertriglyceridemic pancreatitis (AHTGP) is increasing worldwide. AHTGP may be associated with a more severe clinical course and greater mortality than pancreatitis caused by other causes....
4.
Yao J, Ma Q, Shen W, Li L, Hu D
Toxicology
. 2022 Feb;
469:153114.
PMID: 35114310
Silicosis is the most serious occupational pulmonary fibrosis caused by excessive inhalation of silica particles, whereas viable therapeutic choices are constrained. Epigallocatechin gallate (EGCG) presents massive health benefits, but unfortunately...
5.
Zhao X, Liu L, Guo C, Shen W, Cao J, Du F, et al.
Ann Transl Med
. 2021 Aug;
9(13):1063.
PMID: 34422975
Background: High-density lipoprotein (HDL) plays an antiatherogenic role by mediating reverse cholesterol transport (RCT), antioxidation, anti-inflammation, and endothelial cell protection. Recently, series of evidence have shown that HDL can also...
6.
Geng T, Shen W, Wang J, Huang W, Wang Z, Xiao W
Zhongguo Zhong Yao Za Zhi
. 2018 May;
43(7):1384-1391.
PMID: 29728027
Ginkgo terpene lactones, as an important active ingredient from Ginkgo leaves, has high medicinal values and has been widely used in clinics. This article would review the researches both at...
7.
Shen W, Zhang Y, Qiu S, Zhu F, Jia X, Tang D, et al.
Zhongguo Zhong Yao Za Zhi
. 2017 Dec;
42(20):3996-4001.
PMID: 29243439
UPLC-QTOF-MS/MS was used to identify metabolites in rat blood, urine and feces after the administration of n-butanol extract derived from steamed notoginseng. The metabolic process of saponins came from steamed...
8.
Shen W, Zhang H, Qiu S, Wei Y, Zhu F, Wang J, et al.
J Asian Nat Prod Res
. 2017 Mar;
20(7):686-696.
PMID: 28349702
Ginsenosides F and Rg (GF and GRg), two main active components of steamed notoginseng or red ginseng, are dehydrated disaccharide saponins. In this work, biotransformation of ginsenosides F and Rg...
9.
Li X, Shen W, Sun Y, Li W, Sun Z, Liu Y, et al.
Joint Bone Spine
. 2016 Mar;
83(6):695-700.
PMID: 26934991
Objectives: Rheumatoid arthritis (RA) is a heterogenic and systemic autoimmune disease characterized by synovitis and joint structural damage. However, the pathogenesis of RA is still obscure. It has been reported...
10.
Qi R, Li Y, Chen C, Cao Y, Yu M, Xu L, et al.
J Control Release
. 2015 May;
210:160-8.
PMID: 26003044
This work aimed to improve the oral bioavailability and plasma lipid-lowering effect of probucol (PB) by constructing a combined drug delivery system (CDDS) composed of nanostructured lipid carrier (NLC) and...