Wen-Shin Chang
Overview
Explore the profile of Wen-Shin Chang including associated specialties, affiliations and a list of published articles.
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Articles
226
Citations
1451
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Recent Articles
1.
Hung C, Wang Y, Shih H, Liu C, He J, Chen J, et al.
Cancer Genomics Proteomics
. 2025 Feb;
22(2):258-270.
PMID: 39993804
Background/aim: Matrix metalloproteinase-9 (MMP-9) has been associated with the development and progression of breast cancer (BCa). However, the relationship between MMP-9 genetic variants and BCa susceptibility remains contentious and inconclusive....
2.
Shieh P, Shih H, Chuang C, Tsai C, Chang W, Bau M, et al.
Anticancer Res
. 2025 Jan;
45(2):465-471.
PMID: 39890168
Background/aim: Over-expression of matrix metalloproteinase-1 (MMP-1) has been suggested as a biomarker for endometriosis. However, the genetic influence of MMP-1 in the pathogenesis of endometriosis remains unclear, with its role...
3.
Chang S, Chang W, Shih H, Chang C, Wu H, Tsai C, et al.
Cancers (Basel)
. 2025 Jan;
17(2).
PMID: 39857959
Background: This study aimed to investigate the polymorphic genotypes of rs937282, rs937283, rs2279744, and rs769412, as well as the combined effects of genotypes and environmental factors on RCC susceptibility. Methods:...
4.
Yang J, Tsai S, Hsu Y, Bau D, Tsai C, Chang W, et al.
Biomedicine (Taipei)
. 2025 Jan;
14(4):1-14.
PMID: 39777110
The Natural Product Research Laboratory (NPRL) of China Medical University Hospital (CMUH) was established in collaboration with CMUH and Professor Kuo-Hsiung Lee from the University of North Carolina at Chapel...
5.
Kuo C, Tsai C, Chuang F, Wang Y, Mong M, Yang Y, et al.
In Vivo
. 2024 Dec;
39(1):172-179.
PMID: 39740879
Background/aim: Hallux valgus (HV) is the most common deformity of the forefoot. Although HV has been strongly associated with a family history, its genetic underpinnings remain unclear. Few studies have...
6.
Hsu P, Chen C, Tsai H, Chang W, Pei J, Wang Y, et al.
In Vivo
. 2024 Dec;
39(1):152-159.
PMID: 39740875
Background/aim: Genetic polymorphisms in DNA repair mechanisms can modulate overall DNA repair capacity, potentially influencing individual susceptibility to cancer. This study investigated the relationship between polymorphic variations in DNA ligase...
7.
Chen C, Tsai C, Pei J, Tzeng H, Hsu P, Cheng D, et al.
Cancer Genomics Proteomics
. 2024 Dec;
22(1):46-54.
PMID: 39730179
Background/aim: The disruption of cell-cycle control can lead to an imbalance in cell proliferation, often accompanied by genomic instability, which in turn can facilitate carcinogenesis. This study aimed to examine...
8.
Tsai Y, Tsai C, Yang J, Juan Y, Shih H, Bau D, et al.
In Vivo
. 2024 Oct;
38(6):2617-2628.
PMID: 39477405
Background/aim: The administration of contrast agents can adversely affect kidney function. Nevertheless, the nephrotoxicity of iopromide in human renal cells, potential therapeutic agents, and the underlying molecular mechanisms have not...
9.
Fu C, Lee H, Chen J, Yang M, Cheng H, Mong M, et al.
Anticancer Res
. 2024 Oct;
44(11):4833-4841.
PMID: 39477311
Background/aim: In gastric cancer (GCa) tissues, the mRNA and protein levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) are significantly elevated compared to adjacent non-cancerous tissues. Moreover, the abnormal up-regulation of...
10.
Hsia N, Chen H, Tsai H, Hsia T, Hu P, Wang Y, et al.
Anticancer Res
. 2024 Oct;
44(11):4825-4831.
PMID: 39477282
Background/aim: The dysregulation of matrix metalloproteinase (MMP) proteins has been reported to be involved in the etiology of pterygium. However, studies about the role of matrix metalloproteinase-11 (MMP-11) are lacking....