Wen-Jing Xiao
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Explore the profile of Wen-Jing Xiao including associated specialties, affiliations and a list of published articles.
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244
Citations
2329
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Recent Articles
1.
Sun R, Chen P, Xu S, Lu L, Xiao W
Angew Chem Int Ed Engl
. 2025 Feb;
:e202502489.
PMID: 40009445
Despite remarkable advances in photoenzymatic methodologies, the development of photoenzymatic multicomponent reactions remains a significant challenge. In this Highlight, we showcase a recent breakthrough by Prof. Xiaoqiang Huang and co-workers,...
2.
Fu Y, Shi J, Chen P, Xiao W, Lu L
Sci Bull (Beijing)
. 2025 Feb;
PMID: 39979206
No abstract available.
3.
Zhou X, Li Z, Qu W, Zhang Z, Zhang Z, Xiao W, et al.
Angew Chem Int Ed Engl
. 2025 Feb;
:e202424915.
PMID: 39935403
Although the asymmetric α-alkylation of carbonyl compounds with activated olefins has already been established, extending this methodology to less activated or nonactivated olefins remains a significant challenge due to the...
4.
Zhou Z, Fu Y, Zhang C, Li Y, Zhang B, Xiao Y, et al.
J Am Chem Soc
. 2025 Jan;
147(4):3223-3232.
PMID: 39823567
-cycloalkenes are abundant in bioactive natural products and have been used as powerful tools in chemical biology and drug discovery. However, strategies for the modular synthesis of -cycloalkenes, especially planar-chiral...
5.
Wang P, Zhang B, Xiao W, Chen J
Acc Chem Res
. 2024 Nov;
57(23):3433-3448.
PMID: 39535732
ConspectusIn recent years, radical-mediated cross-coupling reactions have emerged as a compelling strategy for achieving a rich diversity in molecular topologies under benign conditions. However, the inherent high reactivity of radicals...
6.
Yuan B, He X, Cheng Y, Xiao W
Org Lett
. 2024 Oct;
26(40):8610-8614.
PMID: 39353052
A visible-light-induced synthesis protocol for silylmonofluoroalkanes is described. The silylation of alkenyl fluorides using (trimethylsilyl)silanes as organosilicon reagents proceeds well under mild conditions via a sequential photoinduced single-electron transfer and...
7.
Shi B, Xiao M, Zhao J, Zhang Z, Xiao W, Lu L
J Am Chem Soc
. 2024 Sep;
146(39):26622-26629.
PMID: 39293040
A Pd-catalyzed asymmetric higher-order dipolar cycloaddition between allenyl carbonates and azadienes is achieved by exploiting novel alkylidene-π-allyl-Pd dipoles. This research provides a modular platform for the synthesis of challenging chiral...
8.
Chen P, Zhang M, Rao L, Li Y, Jia Y, Tan Y, et al.
Sci Bull (Beijing)
. 2024 Aug;
69(22):3516-3524.
PMID: 39183108
Morpholines are widespread in many biologically and catalytically active agents, thus being an important aim of pharmaceutical and synthetic chemists. However, efficient strategies for the catalytic asymmetric synthesis of chiral...
9.
Xiao Y, Fang K, Zhang Z, Zhang C, Li Y, Wang B, et al.
Angew Chem Int Ed Engl
. 2024 Aug;
63(47):e202408426.
PMID: 39177728
Isodesmic reactions, in which chemical bonds are redistributed between substrates and products, provide a general and powerful strategy for both biological and chemical synthesis. However, most isodesmic reactions involve either...
10.
Wang P, Zhang Z, Jiang M, Chen J, Xiao W
Angew Chem Int Ed Engl
. 2024 Jul;
63(43):e202411469.
PMID: 39073195
Radical-involved arylative cross-coupling reactions have recently emerged as an attractive strategy to access valuable aryl-substituted motifs. However, there still exist several challenges such as limited scope of radical precursors/acceptors, and...