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Wen-Bo Xu

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Articles 118
Citations 1160
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Recent Articles
1.
Huang C, Zuo M, Qi X, Gong M, Xu W, Meng S, et al.
BMC Med . 2025 Mar; 23(1):156. PMID: 40075370
Background: Gelsemium elegans (G. elegans) is widely recognized as one of the most toxic plants globally, particularly harmful to humans. Some reports indicate that it is non-toxic to pigs and...
2.
Chai Y, Tian Y, Xu W, Yang B, Wang Z, Chen D, et al.
J Org Chem . 2024 Dec; 90(1):846-852. PMID: 39668696
A refined synthesis of 1,4,2-diazaphospholidine-3,5-dione derivatives was achieved through a cyclization reaction involving Na(OCP) and isocyanates. Na(OCP) was demonstrated to be a relatively stable and safe source of phosphorus, enabling...
3.
Xu W, Wang Y, Meng S, Zhang X, Wang Y, Liu Z
Microbiol Spectr . 2024 Sep; 12(11):e0061124. PMID: 39292002
Importance: Disinfectants are extensively employed across various sectors, such as the food sector. Disinfectants are widely used in various sectors, including the food processing industry, animal husbandry, households, and pharmaceuticals....
4.
Gong M, Long J, Xu W, Huang C, Meng S, Zhang X, et al.
Vet Microbiol . 2024 Aug; 297:110216. PMID: 39151256
Pseudorabies virus (PRV), an α-herpesvirus, induces immunosuppression and can lead to severe neurological diseases. N-methyl-D-aspartate receptor (NMDAR), an important excitatory nerve receptor in the central nervous system, is linked to...
5.
Wang X, Chen D, Wang W, Yang C, Li M, Xu W, et al.
Org Lett . 2024 Apr; 26(17):3575-3580. PMID: 38636450
We introduce switchable chemoselectivity strategies based on the hydrazone phosphaketene intermediate to synthesize three classes of 1,2,4-diazaphosphol derivatives. First, the five-membered heterocyclic P and O anion intermediates acted as nucleophilic...
6.
Wang Y, Zuo M, Xu W, Liu Z
Curr Drug Metab . 2024 Apr; 25(2):157-163. PMID: 38571358
Aim: The aim of this study was to investigate the metabolism of in human, pig, goat and rat liver microsomes and to elucidate the metabolic pathways and cleavage patterns of...
7.
Peng X, Shuang F, Li H, Shao Y, Hu W, Shan J, et al.
Zhongguo Gu Shang . 2023 Nov; 36(11):1021-5. PMID: 38012868
Objective: To compare and analyze the early clinical effect of direct superior approach(DSA) and posterior lateral approach (PLA) in hemiarthroplasty for elderly patients with femoral neck fracture. Methods: The clinical...
8.
Xu W, Lu Z, Mu L
Technol Health Care . 2023 Oct; 32(2):861-871. PMID: 37840505
Background: With the ageing population in China and an increasing number of the elderly developing chronic illnesses, health services for the elderly have become a major concern. They have significant...
9.
Xu W, Li S, Zheng C, Yang Y, Zhang C, Jin C
Med Chem . 2023 Sep; 20(1):40-51. PMID: 37767798
Background: Drug-resistant infections kill hundreds of thousands of people globally every year. In previous work, we found that tri-methoxy- and pyridine-substituted imidazoles show strong antibacterial activities. Objective: The aim of...
10.
Xu W, Tang M, Long J, Wang W, Qin J, Qi X, et al.
Biochem Biophys Res Commun . 2023 Sep; 681:55-61. PMID: 37757667
Gelsemium elegans (G.elegans) is a plant of the Loganiaceae family, known for its indole alkaloids, including gelsemine, koumine, and gelsenicine. Gelsemine and koumine are well-studied active alkaloids with low toxicity,...