Weizhu Yan
Overview
Explore the profile of Weizhu Yan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
158
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Recent Articles
1.
Zheng Y, Xu X, Fu X, Zhou X, Dou C, Yu Y, et al.
Structure
. 2023 Aug;
31(10):1220-1232.e5.
PMID: 37652001
Structural diverse natural products like ribosomally synthesized and posttranslationally modified peptides (RiPPs) display a wide range of biological activities. Currently, the mechanism of an uncommon reaction step during the biosynthesis...
2.
Yan W, Zheng Y, Dou C, Zhang G, Arnaout T, Cheng W
Mol Biomed
. 2022 Dec;
3(1):48.
PMID: 36547804
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a tenacious pathogen that has latently infected one third of the world's population. However, conventional TB treatment regimens are no...
3.
Zheng Y, Yan W, Dou C, Zhou D, Chen Y, Jin Y, et al.
MedComm (2020)
. 2022 Mar;
3(1):e99.
PMID: 35281791
, a food-borne Gram-positive pathogen, often causes diseases such as gastroenteritis, bacterial sepsis, and meningitis. Newly discovered extracellular electron transfer (EET) from plays critical roles in the generation of redox...
4.
Dou C, Long Z, Li S, Zhou D, Jin Y, Zhang L, et al.
Cell Res
. 2022 Feb;
32(3):302-314.
PMID: 35110668
Methanobactins (Mbns) are a family of copper-binding peptides involved in copper uptake by methanotrophs, and are potential therapeutic agents for treating diseases characterized by disordered copper accumulation. Mbns are produced...
5.
Yan W, Zheng Y, Zeng X, He B, Cheng W
Signal Transduct Target Ther
. 2022 Jan;
7(1):26.
PMID: 35087058
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The discovery of therapy reagents for treating COVID-19...
6.
Ren S, de Kok N, Gu Y, Yan W, Sun Q, Chen Y, et al.
Cell Rep
. 2021 May;
35(7):109182.
PMID: 34010650
No abstract available.
7.
Ren S, de Kok N, Gu Y, Yan W, Sun Q, Chen Y, et al.
Cell Rep
. 2020 Oct;
33(3):108294.
PMID: 33086053
The UbiA superfamily of intramembrane prenyltransferases catalyzes an isoprenyl transfer reaction in the biosynthesis of lipophilic compounds involved in cellular physiological processes. Digeranylgeranylglyceryl phosphate (DGGGP) synthase (DGGGPase) generates unique membrane...
8.
Hu B, Wang Y, Sun S, Yan W, Zhang C, Luo D, et al.
Angew Chem Int Ed Engl
. 2019 May;
58(23):7835-7839.
PMID: 31037810
2'-Deoxynucleoside 5'-(alpha-P-seleno)-triphosphates (dNTPαSe) have been conveniently synthesized using a protection-free, one-pot strategy. One of two diastereomers of each dNTPαSe can be efficiently recognized by DNA polymerases, while the other is...
9.
Zhang C, Qin S, Hu B, Lv J, Yang Z, Yan W, et al.
Nucleosides Nucleotides Nucleic Acids
. 2019 Mar;
38(8):567-577.
PMID: 30922168
Strong intermolecular interaction can prevent an organic molecule from dissolving in a reaction solution, thereby jeopardizing its reactivity and usefulness. Nucleobases and nucleosides (especially many purines and their derivatives) are...