Weizhou Zhang
Overview
Explore the profile of Weizhou Zhang including associated specialties, affiliations and a list of published articles.
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Articles
111
Citations
4263
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Recent Articles
1.
Ducharme J, Carelock M, Schonk M, Al-Zaeed N, Zhang W, Judge S, et al.
Am J Physiol Cell Physiol
. 2025 Feb;
PMID: 39993009
Cancer cachexia is the involuntary loss of body and skeletal muscle mass, which negatively impacts physical function, quality of life, treatment tolerance, and survival. Skeletal muscles of cachectic people and...
2.
Carelock M, Master R, Kim M, Jin Z, Wang L, Maharjan C, et al.
Life Med
. 2025 Jan;
2(3):lnad019.
PMID: 39872303
Immune checkpoint inhibitors (ICIs) use antibodies that block cell surface immune checkpoint proteins with great efficacy in treating immunogenic or "immune hot" tumors such as melanoma, kidney, and lung adenocarcinoma....
3.
Han S, Zhuang H, Diao Y, Segal M, Tithi T, Zhang W, et al.
Autophagy Rep
. 2025 Jan;
3(1).
PMID: 39871963
Abnormal autophagy regulation is implicated in lupus and other autoimmune diseases. We investigated autophagy in the murine pristane-induced lupus model. Pristane causes monocyte/macrophage-mediated endoplasmic reticulum (ER) stress in lung endothelial...
4.
Cheng T, Fu D, Falzarano S, Zhang R, Datta S, Zhang W, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769193
This hypothesis-generating study aims to examine the extent to which computed tomography-assessed body composition phenotypes are associated with immune and phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathways in breast...
5.
Bian T, Lynch A, Ballas K, Mamallapalli J, Freeman B, Scala A, et al.
ACS Pharmacol Transl Sci
. 2024 Nov;
7(11):3502-3517.
PMID: 39539272
Tobacco smoke remains a serious global issue, resulting in serious health complications, contributing to the onset of numerous preventive diseases and imposing significant health burdens. Despite regulatory policies and cessation...
6.
Kim M, Borcherding N, Song W, Kolb R, Zhang W
Front Vet Sci
. 2024 Oct;
11:1434617.
PMID: 39376916
Introduction: Single-cell RNA sequencing (scRNA-seq) has become an essential tool for uncovering the complexities of various physiological and immunopathological conditions in veterinary medicine. However, there is currently limited information on...
7.
Si Y, Lee C, Hwang Y, Yun J, Cheng W, Cho C, et al.
Nat Methods
. 2024 Sep;
21(10):1843-1854.
PMID: 39266749
Spatial transcriptomics (ST) technologies have advanced to enable transcriptome-wide gene expression analysis at submicron resolution over large areas. However, analysis of high-resolution ST is often challenged by complex tissue structure,...
8.
Erwin N, De U, Xiao Y, Wang L, Maharjan C, Pan X, et al.
bioRxiv
. 2024 Sep;
PMID: 39253438
Proteolysis targeting chimeras (PROTACs) are an emerging targeted cancer therapy approach, but wide-spread clinical use of PROTAC is limited due to poor cell targeting and penetration, and instability in vivo....
9.
Jin Z, De U, Tithi T, Kleberg J, Nataraj A, Jolley E, et al.
Cancer Res Commun
. 2024 Aug;
4(8):2242-2254.
PMID: 39105498
Significance: Our data indicate angiopoietin-like 4 (ANGPTL4) acts as a tumor suppressor in clear cell renal cell carcinoma via regulating lipid metabolism and identifies a cohort of patients with lower...
10.
Dupere-Richer D, Riva A, Barwick B, Maji S, Casellas Roman H, Li J, et al.
Blood
. 2024 Jul;
144(14):1508-1520.
PMID: 39046770
The histone H3 at lysine 27 (H3K27) demethylase lysine demethylase 6A (KDM6A) is a tumor suppressor in multiple cancers, including multiple myeloma (MM). We created isogenic MM cells disrupted for...