Weixin Tang
Overview
Explore the profile of Weixin Tang including associated specialties, affiliations and a list of published articles.
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28
Citations
1424
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Recent Articles
1.
Yan H, Tan X, Zou S, Sun Y, Ke A, Tang W
Nat Chem Biol
. 2024 Jul;
20(12):1617-1628.
PMID: 38977787
OMEGA RNA (ωRNA)-guided endonuclease IscB, the evolutionary ancestor of Cas9, is an attractive system for in vivo genome editing because of its compact size and mechanistic resemblance to Cas9. However,...
2.
Yan H, Tang W
Nat Chem Biol
. 2024 Jul;
20(10):1361-1370.
PMID: 38969862
Programmed RNA editing presents an attractive therapeutic strategy for genetic disease. In this study, we developed bacterial deaminase-enabled recoding of RNA (DECOR), which employs an evolved Escherichia coli transfer RNA...
3.
Xiao Y, Chen Y, Zou Z, Ye C, Dou X, Wu J, et al.
Nat Methods
. 2024 Jan;
21(2):247-258.
PMID: 38200227
RNA-binding proteins (RBPs) regulate diverse cellular processes by dynamically interacting with RNA targets. However, effective methods to capture both stable and transient interactions between RBPs and their RNA targets are...
4.
Xiao Y, Wu Y, Tang W
Nat Biotechnol
. 2024 Jan;
42(9):1442-1453.
PMID: 38168987
Adenine base editors (ABEs) are precise gene-editing agents that convert A:T pairs into G:C through a deoxyinosine intermediate. Existing ABEs function most effectively when the target A is in a...
5.
Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, et al.
Nat Chem Biol
. 2023 Dec;
20(1):129.
PMID: 38040979
No abstract available.
6.
Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, et al.
Nat Chem Biol
. 2023 Jul;
19(11):1384-1393.
PMID: 37400536
Compact CRISPR-Cas systems offer versatile treatment options for genetic disorders, but their application is often limited by modest gene-editing activity. Here we present enAsCas12f, an engineered RNA-guided DNA endonuclease up...
7.
8.
Meng H, Chen Z, Chen L, Tang W, He F, Yan X, et al.
Clin Toxicol (Phila)
. 2023 Mar;
61(4):270-275.
PMID: 36919497
Background: The mushroom is reported to cause acute liver injury. It is found in Southern China, and has been previously associated with a high incidence of mortality. Methods: We described...
9.
Xiao Y, Liu S, Ge R, Wu Y, He C, Chen M, et al.
Nat Biotechnol
. 2023 Jan;
41(7):993-1003.
PMID: 36593412
N-methyladenosine (mA), the most abundant internal messenger RNA modification in higher eukaryotes, serves myriad roles in regulating cellular processes. Functional dissection of mA is, however, hampered in part by the...
10.
Xu P, Wang R, Ding T, Tang W, Zhang C
ACS Omega
. 2022 Mar;
7(10):9044-9052.
PMID: 35309425
As one of the simplest polyols with chemical properties of alcohol, ethylene glycol is considered as a renewable energy source and a model fuel for pyrolysis oil. In this work,...