Weining Lu
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Explore the profile of Weining Lu including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1948
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Recent Articles
1.
Kumar S, Fan X, Pattam H, Yan K, Liaw E, Ji J, et al.
bioRxiv
. 2025 Mar;
PMID: 40060690
Author Summary: Hydroureter and hydronephrosis are common congenital anomalies with high incidence (1:100 to 1:500) that can lead to obstructive uropathy and renal failure in the pediatric population. Mowat-Wilson Syndrome...
2.
Lu W, Tang Y, Liu Y, Lin S, Shuai Q, Liang B, et al.
Brief Bioinform
. 2024 Jul;
25(5).
PMID: 39073831
Histone modifications, known as histone marks, are pivotal in regulating gene expression within cells. The vast array of potential combinations of histone marks presents a considerable challenge in decoding the...
3.
Laudon A, Wang Z, Zou A, Sharma R, Ji J, Kim C, et al.
bioRxiv
. 2024 Jul;
PMID: 38948787
Background: Transmission electron microscopy (TEM) images can visualize kidney glomerular filtration barrier ultrastructure, including the glomerular basement membrane (GBM) and podocyte foot processes (PFP). Podocytopathy is associated with glomerular filtration...
4.
Kumar S, Fan X, Rasouly H, Sharma R, Salant D, Lu W
JCI Insight
. 2022 Nov;
8(1).
PMID: 36445780
FOXD1+ cell-derived stromal cells give rise to pericytes and fibroblasts that support the kidney vasculature and interstitium but are also major precursors of myofibroblasts. ZEB2 is a SMAD-interacting transcription factor...
5.
Wu S, Jiang H, Chen Z, Lu W, Chen Q
Evid Based Complement Alternat Med
. 2022 Oct;
2022:5340933.
PMID: 36212968
Background: Pan Ji Sheng Formula is a Chinese medicine formula that enables heat-free detoxification as well as anti-inflammatory and immune-boosting properties. This formula contains eight herbs. Its underlying mechanism is...
6.
Wu C, Lim T, Wang C, Seltzsam S, Zheng B, Schierbaum L, et al.
Eur Urol Open Sci
. 2022 Oct;
44:106-112.
PMID: 36185583
Background: Congenital anomalies of the kidneys and urinary tract (CAKUT) are the most common cause of chronic kidney disease among children and adults younger than 30 yr. In our previous...
7.
Beck Jr L, Berasi S, Copley J, Gorman D, Levy D, Lim C, et al.
Kidney Int Rep
. 2021 Jun;
6(6):1629-1633.
PMID: 34169203
Introduction: Focal segmental glomerulosclerosis (FSGS) is characterized by proteinuria and a histologic pattern of glomerular lesions of diverse etiology that share features including glomerular scarring and podocyte foot process effacement....
8.
Connaughton D, Dai R, Owen D, Marquez J, Mann N, Graham-Paquin A, et al.
Am J Hum Genet
. 2020 Sep;
107(4):727-742.
PMID: 32891193
Congenital anomalies of the kidney and urinary tract (CAKUT) constitute one of the most frequent birth defects and represent the most common cause of chronic kidney disease in the first...
9.
Pisarek-Horowitz A, Fan X, Kumar S, Rasouly H, Sharma R, Chen H, et al.
Am J Pathol
. 2020 Mar;
190(4):799-816.
PMID: 32220420
Roundabout guidance receptor 2 (ROBO2) plays an important role during early kidney development. ROBO2 is expressed in podocytes, inhibits nephrin-induced actin polymerization, down-regulates nonmuscle myosin IIA activity, and destabilizes kidney...
10.
Huang M, Zhu S, Huang H, He J, Tsuji K, Jin W, et al.
J Am Soc Nephrol
. 2019 Oct;
30(11):2073-2090.
PMID: 31653783
Background: Necroptosis is a newly discovered cell death pathway that plays a critical role in AKI. The involvement of integrin-linked kinase (ILK) in necroptosis has not been studied. Methods: We...