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Weinian Liao

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Articles 12
Citations 69
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Recent Articles
1.
Du C, Liu C, Yu K, Zhang S, Fu Z, Chen X, et al.
Cell Stem Cell . 2024 Aug; 31(10):1484-1500.e9. PMID: 39181130
Hematopoietic stem cells (HSCs) employ a very unique metabolic pattern to maintain themselves, while the spectrum of their metabolic adaptations remains incompletely understood. Here, we uncover a distinct and heterogeneous...
2.
Zhang Y, Chen X, Wang X, Chen J, Du C, Wang J, et al.
Stem Cell Res Ther . 2024 Jul; 15(1):222. PMID: 39039566
With the widespread application of nuclear technology across various fields, ionizing radiation-induced injuries are becoming increasingly common. The bone marrow (BM) hematopoietic tissue is a primary target organ of radiation...
3.
Liao W, Chen X, Zhang S, Chen J, Liu C, Yu K, et al.
Cell Commun Signal . 2024 May; 22(1):292. PMID: 38802843
Background: Hematopoietic stem cell (HSC) regeneration underlies hematopoietic recovery from myelosuppression, which is a life-threatening side effect of cytotoxicity. HSC niche is profoundly disrupted after myelosuppressive injury, while if and...
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5.
Wang Y, Ran L, Lan Q, Liao W, Wang L, Wang Y, et al.
Kidney Int . 2023 Sep; 104(5):956-974. PMID: 37673285
After acute kidney injury (AKI), renal tubular epithelial cells (RTECs) are pathologically characterized by intracellular lipid droplet (LD) accumulation, which are involved in RTEC injury and kidney fibrosis. However, its...
6.
Liao W, Liu C, Yang K, Chen J, Wu Y, Zhang S, et al.
Cell Mol Immunol . 2023 Aug; 20(10):1216-1231. PMID: 37644165
Although DNA mutation drives stem cell aging, how mutation-accumulated stem cells obtain clonal advantage during aging remains poorly understood. Here, using a mouse model of irradiation-induced premature aging and middle-aged...
7.
Liu C, Liao W, Chen J, Yu K, Wu Y, Zhang S, et al.
Redox Biol . 2023 Mar; 62:102661. PMID: 36906952
There is growing appreciation that hematopoietic alterations underpin the ubiquitous detrimental effects of metabolic disorders. The susceptibility of bone marrow (BM) hematopoiesis to perturbations of cholesterol metabolism is well documented,...
8.
Lan Q, Du C, Xiong J, Wu Y, Liao W, Liu C, et al.
J Thromb Haemost . 2022 Sep; 20(12):2972-2987. PMID: 36087344
Background: Thrombosis and hemorrhage as two opposite pathologies are prevalent within the chronic kidney disease (CKD) population. Platelet homeostasis, which positions centrally in their pathogenesis, varies among the CKD population,...
9.
Wu Y, Liao W, Chen J, Liu C, Zhang S, Yu K, et al.
Nutrients . 2022 Aug; 14(16). PMID: 36014901
Myelosuppression is a common and intractable side effect of cancer therapies including radiotherapy and chemotherapy, while the underlying mechanism remains incompletely understood. Here, using a mouse model of radiotherapy-induced myelosuppression,...
10.
Du C, Wang X, Wu Y, Liao W, Xiong J, Zhu Y, et al.
Cell Rep . 2022 Feb; 38(7):110392. PMID: 35172146
The composition and origin of extrinsic cues required for hematopoietic stem cell (HSC) maintenance are incompletely understood. Here we identify renal Klotho and inorganic phosphate (Pi) as extrinsic factors that...