Kuan Yu
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Explore the profile of Kuan Yu including associated specialties, affiliations and a list of published articles.
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22
Citations
163
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Recent Articles
1.
Gu Y, Mi Y, Cao Y, Yu K, Zhang Z, Lian P, et al.
Cell Biosci
. 2025 Feb;
15(1):23.
PMID: 39972363
Background: Colorectal liver metastasis (CRLM) is the main cause of death in colorectal cancer (CRC) patients worldwide. In the initial stage of metastasis, primary tumors provide the necessary conditions for...
2.
Du C, Liu C, Yu K, Zhang S, Fu Z, Chen X, et al.
Cell Stem Cell
. 2024 Aug;
31(10):1484-1500.e9.
PMID: 39181130
Hematopoietic stem cells (HSCs) employ a very unique metabolic pattern to maintain themselves, while the spectrum of their metabolic adaptations remains incompletely understood. Here, we uncover a distinct and heterogeneous...
3.
Liao W, Chen X, Zhang S, Chen J, Liu C, Yu K, et al.
Cell Commun Signal
. 2024 May;
22(1):292.
PMID: 38802843
Background: Hematopoietic stem cell (HSC) regeneration underlies hematopoietic recovery from myelosuppression, which is a life-threatening side effect of cytotoxicity. HSC niche is profoundly disrupted after myelosuppressive injury, while if and...
4.
Cao Y, Yu K, Zhang Z, Gu Y, Gu Y, Li W, et al.
Clin Transl Med
. 2024 Feb;
14(2):e1578.
PMID: 38356419
Background And Aims: In gastric cancer, the response rate of programmed cell death protein-1 (PD-1) inhibitor is far from satisfactory, indicating additional nonredundant pathways might hamper antitumour immunity. V-domain immunoglobulin...
5.
Du C, Wu Y, Yang K, Liao W, Ran L, Liu C, et al.
Mil Med Res
. 2023 Dec;
10(1):66.
PMID: 38111039
Background: The essential roles of platelets in thrombosis have been well recognized. Unexpectedly, thrombosis is prevalent during thrombocytopenia induced by cytotoxicity of biological, physical and chemical origins, which could be...
6.
Liu C, Liao W, Chen J, Yu K, Wu Y, Zhang S, et al.
Redox Biol
. 2023 Oct;
67:102924.
PMID: 37839953
No abstract available.
7.
Liao W, Liu C, Yang K, Chen J, Wu Y, Zhang S, et al.
Cell Mol Immunol
. 2023 Aug;
20(10):1216-1231.
PMID: 37644165
Although DNA mutation drives stem cell aging, how mutation-accumulated stem cells obtain clonal advantage during aging remains poorly understood. Here, using a mouse model of irradiation-induced premature aging and middle-aged...
8.
Liu C, Liao W, Chen J, Yu K, Wu Y, Zhang S, et al.
Redox Biol
. 2023 Mar;
62:102661.
PMID: 36906952
There is growing appreciation that hematopoietic alterations underpin the ubiquitous detrimental effects of metabolic disorders. The susceptibility of bone marrow (BM) hematopoiesis to perturbations of cholesterol metabolism is well documented,...
9.
Vasilev V, Spessert L, Yu K, Maimone T
J Am Chem Soc
. 2022 Aug;
144(36):16332-16337.
PMID: 36043948
From both structural and functional perspectives, the large family of daphnane diterpene orthoesters (DDOs) represent a truly remarkable class of natural products. As potent lead compounds for the treatment of...
10.
Wu Y, Liao W, Chen J, Liu C, Zhang S, Yu K, et al.
Nutrients
. 2022 Aug;
14(16).
PMID: 36014901
Myelosuppression is a common and intractable side effect of cancer therapies including radiotherapy and chemotherapy, while the underlying mechanism remains incompletely understood. Here, using a mouse model of radiotherapy-induced myelosuppression,...