Weimiao Yu
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Explore the profile of Weimiao Yu including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Ong K, Young D, Sulaiman S, Shamsuddin S, Mohd Zain N, Hashim H, et al.
Sci Rep
. 2022 Mar;
12(1):4433.
PMID: 35292654
White matter lesions (WML) underlie multiple brain disorders, and automatic WML segmentation is crucial to evaluate the natural disease course and effectiveness of clinical interventions, including drug discovery. Although recent...
12.
Teh Y, Chooi M, Liu D, Kwok I, Lai G, Ayub Ow Yong L, et al.
Sci Adv
. 2022 Mar;
8(9):eabj4641.
PMID: 35245124
Circulating Ly6C monocytes often undergo cellular death upon exhaustion of their antibacterial effector functions, which limits their capacity for subsequent macrophage differentiation. This shrouds the understanding on how the host...
13.
Zhu X, Li X, Ong K, Zhang W, Li W, Li L, et al.
Nat Commun
. 2021 Jun;
12(1):3541.
PMID: 34112790
Technical advancements significantly improve earlier diagnosis of cervical cancer, but accurate diagnosis is still difficult due to various factors. We develop an artificial intelligence assistive diagnostic solution, AIATBS, to improve...
14.
Young D, Fazel Darbandi S, Schwartz G, Bonzell Z, Yuruk D, Nojima M, et al.
Elife
. 2021 Feb;
10.
PMID: 33570495
3D imaging data necessitate 3D reference atlases for accurate quantitative interpretation. Existing computational methods to generate 3D atlases from 2D-derived atlases result in extensive artifacts, while manual curation approaches are...
15.
Liu Z, Parikh B, Tan Q, Wong D, Ong K, Yu W, et al.
Stem Cell Reports
. 2021 Jan;
16(2):237-251.
PMID: 33450191
Recent trials of retinal pigment epithelium (RPE) transplantation for the treatment of disorders such as age-related macular degeneration have been promising. However, limitations of existing strategies include the uncertain survival...
16.
Paknezhad M, Loh S, Choudhury Y, Koh V, Yong T, Tan H, et al.
BMC Bioinformatics
. 2020 Dec;
21(1):558.
PMID: 33276732
Background: High resolution 2D whole slide imaging provides rich information about the tissue structure. This information can be a lot richer if these 2D images can be stacked into a...
17.
Young D, Duhn C, Gilson M, Nojima M, Yuruk D, Kumar A, et al.
Curr Protoc Neurosci
. 2020 Sep;
94(1):e104.
PMID: 32981139
MagellanMapper is a software suite designed for visual inspection and end-to-end automated processing of large-volume, 3D brain imaging datasets in a memory-efficient manner. The rapidly growing number of large-volume, high-resolution...
18.
Tan E, Hopkins R, Lim C, Jamuar S, Ong C, Thoon K, et al.
J Clin Invest
. 2020 Aug;
130(11):5817-5832.
PMID: 32750042
Although IKK-β has previously been shown as a negative regulator of IL-1β secretion in mice, this role has not been proven in humans. Genetic studies of NF-κB signaling in humans...
19.
Gole L, Yeong J, Lim J, Ong K, Han H, Thike A, et al.
Breast Cancer Res
. 2020 May;
22(1):42.
PMID: 32375854
Background: Stromal and collagen biology has a significant impact on tumorigenesis and metastasis. Collagen is a major structural extracellular matrix component in breast cancer, but its role in cancer progression...
20.
Xue K, Zhao X, Zhang Z, Qiu B, Tan Q, Ong K, et al.
Biomater Sci
. 2019 Aug;
7(11):4603-4614.
PMID: 31436780
Anti-vascular endothelial growth factor (anti-VEGF) proteins are the gold-standard treatment for posterior eye segment proliferative vascular diseases such as Age-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR). However, the standard...